Skip to main content
SpringerLink
Log in

Fractional scanned carbon dioxide laser induces collagen remodelling in murine dermis

  • Laser Methods in Chemistry, Biology, and Medicine
  • Published:
Laser Physics

Abstract

Resurfacing using a fractional CO2 laser shows an important promise in the therapy on photoaged skin. The present study investigated that fractional CO2 laser with a special sequential scanned manner induced the collagen remodelling in murine dermis. The results showed that laser resulted in the improvement of elasticity and histology in the murine dermis, meaning laser efficacy depends on both of the collagen formation and organization. We further investigated the relations between skin elasticity and type I, and type III collagen. These data demonstrated that laser could significantly lead to the collagen remodelling in murine dermis and induce neocollagenisis as a mode of resurfacing.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. S. Alster and S. Garg, Plast. Reconstr. Surg. 98, 791 (1996).

    Article  Google Scholar 

  2. R. E. Fitzpatrick, J. N. Ruiz-Esparza, and M. P. Goldman, J. Dermatol. Surg. Oncol. 17, 340 (1991).

    Google Scholar 

  3. L. J. Bernstein, A. N. Kauvar, M. C. Grossman, and R. G. Geronemus, Dermatol. Surg. 23, 519 (1997).

    Article  Google Scholar 

  4. C. A. Nanni and T. S. Alster, Dermatol. Surg. 24, 315 (1998).

    Article  Google Scholar 

  5. C. Weinstein, Clin. Plast. Surg. 25, 109 (1998).

    Google Scholar 

  6. W. Manuskiatti, R. E. Fitzpatrick, and M. R. Goldman, J. Am. Acad. Dermatol. 40, 401 (1999).

    Article  Google Scholar 

  7. D. Manstein, G. S. Herron, R. K. Sink, H. Tanner, and R. R. Anderson, Laser. Surg. Med. 34, 426 (2004).

    Article  Google Scholar 

  8. H. J. Laubach, Z. Tannous, R. R. Anderson, and D. Manstein, Lasers. Surg. Med. 38, 142 (2006).

    Article  Google Scholar 

  9. R. G. Geronemus, Lasers. Surg. Med. 38, 169 (2006).

    Article  Google Scholar 

  10. A. M. Chapas, L. Brightman, S. Sukal, E. Hale, D. Daniel, L. J. Bernstein, and R.G Geronemus, Lasers. Surg. Med. 40, 381 (2008).

    Article  Google Scholar 

  11. I. Uhoda, N. Faska, C. Robert, G. Cauwenbergh, and G. F. Pierard, Skin. Res. Technol. 8, 164 (2002).

    Article  Google Scholar 

  12. E. V. Ross, J. R. McKinlay, and R. R. Anderson, Arch. Dermatol. 135, 444 (1999).

    Article  Google Scholar 

  13. F. Verzar and I. Z. Nagy, Gerontologia 16, 77 (1970).

    Article  Google Scholar 

  14. I. Z. Nagy, V. N. Toth, and F. Vezar, Connect. Tissue. Res. 2, 265 (1974).

    Article  Google Scholar 

  15. E. V. Ross, S. S. Yashar, G. S. Naseef, D. J. Barnette, M. Skrobal, J. Grevelink, and R. R. Anderson, Dermatol. Surg. 25, 851 (1999).

    Article  Google Scholar 

  16. E. V. Ross, G. S. Naseef, J. R. McKinlay, D. J. Barnette, M. Skrobal, J. Grevelink, and R. R. Anderson, J. Am. Acad. Dermatol. 42, 92 (2000).

    Article  Google Scholar 

  17. A. N. Kauvar, H. A. Waldorf, and R. G. Geronemus, Dermatol. Surg. 22, 343 (1996).

    Article  Google Scholar 

  18. J. Cotton, A. F. Hood, R. Gonin, W. H. Beesen, and C. W. Hanke, Arch. Dermatol. 132, 425 (1996).

    Article  Google Scholar 

  19. L. B. Alexander, H. Mussarrat, P. Robert, and J. G. David, Dermatol. Surg. 35, 222 (2009).

    Article  Google Scholar 

  20. T. Fujimura, Y. Takema, S. Moriwaki, K. Tsukahara, G. Imokawa, A. Yamada, and S. Imayama, Lasers. Surg. Med. 28, 348 (2001).

    Article  Google Scholar 

  21. M. Fluck, M.-N. Giraud, V. Tunc, and M. Chiquet, Biochim. Biophys. Acta. 1593, 239 (2003).

    Article  Google Scholar 

  22. J. Varani, L. Schuger, M. K. Dame, C. Leonard, S. E. Fligiel, S. Kang, G. J. Fisher, and J. J. Voorhees, J. Invest. Dermatol. 122, 1471 (2004).

    Article  Google Scholar 

  23. H. Cook, K. J. Davies, K. G. Harding, and D. W. Thomas, J. Invest. Dermatol. 115, 225 (2000).

    Article  Google Scholar 

  24. R. Moseley, J. E. Stewart, P. Stephens, R. J. Waddington, and D. W. Thomas, Br. J. Dermatol. 150, 401 (2004).

    Article  Google Scholar 

  25. L. Baumann, J. Kaufman, and S. Saghari, Dermatol. Ther. 19, 134 (2006).

    Article  Google Scholar 

  26. J. Varani, M. K. Dame, L. Rittie, S. E. Fligiel, S. Kang, G. J. Fisher, and J. J. Voorhees, Am. J. Pathol. 168, 1861 (2006).

    Article  Google Scholar 

  27. C. R. Lovell, K. A. Smolenski, V. C. Duance, N. D. Light, S. Young, and M. Dyson, Br. J. Dermatol. 117, 419 (1987).

    Article  Google Scholar 

  28. C. Stelzer, E. Uhlmann, M. Meinke, J. Lademann, and U. Hansen, Laser Phys. Lett. 6, 311 (2009).

    Article  ADS  Google Scholar 

  29. J. Kato, H. Hatayama, H. Miyazaki, G. Akashi, K. Moriya, A. Inoue, and Y. Hirai, Laser Phys. Lett. 5, 316 (2008).

    Article  ADS  Google Scholar 

  30. S. M. Zhuo, J. X. Chen, S. S. Xie, L. Q. Zheng, Z. B. Hong, and X. S. Jiang, Laser Phys. Lett. 6, 764 (2009).

    Article  ADS  Google Scholar 

  31. T. Luo, J. X. Chen, S. M. Zhuo, K. C. Lu, X. S. Jiang, and Q. G. Liu, Laser Phys. 19, 478 (2009).

    Article  ADS  Google Scholar 

  32. C. F. Oliveira, J. Hebling, P. P. C. Souza, N. T. Sacono, F. R. Lessa, R. F. Z. Lizarelli, and C. A. S. Costa, Laser Phys. Lett. 5, 680 (2008).

    Article  ADS  Google Scholar 

  33. S. M. Zhuo, J. X. Chen, X. S. Jiang, K. C. Lu, and S. S. Xie, Laser Phys. Lett. 5, 614 (2008).

    Article  ADS  Google Scholar 

  34. V. Czaika, A. Alborova, W. Sterry, J. Lademann, and S. Koch, Laser Phys. Lett. 7, 685 (2010).

    Article  ADS  Google Scholar 

  35. S. Bal, A. C. Kruithof, H. Liebl, M. Tomerius, J. Bouwstra, J. Lademann, and M. Meinke, Laser Phys. Lett. 7, 242 (2010).

    Article  ADS  Google Scholar 

  36. C. Antoniou, J. Lademann, H. Richter, S. Astner, A. Patzelt, L. Zastrow, W. Sterry, and S. Koch, Laser Phys. Lett. 6, 393 (2009).

    Article  ADS  Google Scholar 

  37. S. Chen, X. S. Jiang, J. X. Chen, X. Q. Zhu, L. Q. Zheng, S. M. Zhuo, H. Q. Yang, and D. J. Wang, Laser Phys. 20, 900 (2010).

    Article  ADS  Google Scholar 

  38. E. Sobol, O. Zakharkina, A. Baskov, A. Shekhter, I. Borschenko, A. Guller, V. Baskov, A. Omelchenko, and A. Sviridov, Laser Phys. 19, 825 (2009).

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute for Laser Medicine and Bio-Photonics, Department of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China

    X. Jiang & Q. S. Ren

  2. Institute of Dermatology and Department of Dermatology at NO. 1 Hospital, Anhui Medical University, Hefei, Anhui, 230032, China

    H. M. Ge

  3. Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, China, Hefei, Anhui, 230032, China

    J. J. Liu

Authors
  1. X. Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. M. Ge
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. J. Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Q. S. Ren
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Q. S. Ren.

Additional information

Original Text © Astro, Ltd., 2011.

The article is published in the original.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jiang, X., Ge, H.M., Liu, J.J. et al. Fractional scanned carbon dioxide laser induces collagen remodelling in murine dermis. Laser Phys. 21, 548–553 (2011). https://doi.org/10.1134/S1054660X11050124

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1054660X11050124

Keywords

Search

Navigation