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Investigation of the Structure of a Dimyristoyl Phosphatidylcholine Bilayer via Neutron Reflectometry

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Abstract

The method of bilayer deposition on the surface of silicon from a solution of unilamellar vesicles is tested via neutron reflectometry. A neutron reflectivity curve from the lipid bilayer of the dimyristoyl phosphatidylcholine (DMPC) is acquired in an excess of water. Analysis of the reflectivity curves is carried out in the step-function approximation of the distribution of the neutron scattering length density at the silicon–liquid interface. The lipid bilayer thickness is calculated as 45 ± 6 Å at a temperature of 30°C.

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Funding

This work was supported by the Russian Science Foundation (grant no. 14-12-00516).

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Authors and Affiliations

  1. Joint Institute for Nuclear Research, 141980, Dubna, Russia

    M. A. Kiselev & D. N. Selyakov

  2. Dubna State University, 141982, Dubna, Russia

    M. A. Kiselev

  3. Moscow State University, 119991, Moscow, Russia

    M. A. Kiselev

Authors
  1. M. A. Kiselev
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  2. D. N. Selyakov
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Correspondence to M. A. Kiselev.

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Kiselev, M.A., Selyakov, D.N. Investigation of the Structure of a Dimyristoyl Phosphatidylcholine Bilayer via Neutron Reflectometry. J. Surf. Investig. 15, 327–331 (2021). https://doi.org/10.1134/S1027451021020245

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  • DOI: https://doi.org/10.1134/S1027451021020245

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