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Immobilization of an Antibacterial Compound from Streptomyces sp. onto Multi-Walled Carbon Nanotubes

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Abstract

The pigment compound 2,5-di-tert-butyl-1,4-benzoquinone (DTBBQ) was selectively immobilized on multi-walled carbon nanotube (MWNT) during the electrochemical oxidation process. The glassy carbon electrode (GCE)/Q/MWNT showed a stable redox peak at 50 mV vs. Ag/AgCl in pH 7. Antibacterial activity of DTBBQ immobilized on multi-walled nanotube (hybrid DTBBQ/MWNT) against Bacillus cereus (MTCC 1168) and Escherichia coli (MTCC 2401) showed an enhanced minimum inhibitory concentration at 0.78 and 1.5 µg/mL against the bacterial pathogens. The results evidently show the immobilization of DTBBQ on CNT with enhanced redox response peaks observed at –0.01 V (Epa) and –0.2V (Epc) vs. Ag/AgCl. This new electrochemical method to immobilize the drugs onto MWNT is successfully demonstrated and would have potential applications as a remedy for removal of harmful microbes from the environment.

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ACKNOWLEDGMENTS

The authors are grateful to the management of VIT University for providing the facilities to carry out this study.

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Authors and Affiliations

  1. Sun-yatsen University, School of Marine Science, Guangzhou, China

    Jannu Vinay Gopal

  2. Department of Polymer Science and Engineering, Department of IT Convergence, Korea National University of Transportation, 23769, Chungju, South Korea

    Modigunta Jeevan Kumar Reddy

  3. Vellore Institute of Technology, School of Biosciences and Technology, 632014, Vellore, India

    Krishnan Kannabiran

Authors
  1. Jannu Vinay Gopal
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  2. Modigunta Jeevan Kumar Reddy
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  3. Krishnan Kannabiran
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Correspondence to Jannu Vinay Gopal, Modigunta Jeevan Kumar Reddy or Krishnan Kannabiran.

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Jannu Vinay Gopal, Reddy, M.J. & Kannabiran, K. Immobilization of an Antibacterial Compound from Streptomyces sp. onto Multi-Walled Carbon Nanotubes. Russ J Electrochem 57, 92–96 (2021). https://doi.org/10.1134/S1023193521010043

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  • DOI: https://doi.org/10.1134/S1023193521010043

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