Abstract
Electrosynthesis of 3,4-diphenylhexane-3,4-diol is performed by the propiophenone reduction in a 0.2 M Et4NBr solution in dimethylformamide under the conditions of diaphragmless galvanostatic electrolysis using Pt (Cu, Ni) cathode and Mg (Zn) anode, at a current of 0.2 A and a temperature of 30°C. The process parameters are optimized, and a preparative method is developed for producing a mixture of meso/dl-isomers of the desired product in a 1/3.3 ratio with an overall yield of 76% as calculated per loaded propiophenone at its 90-% conversion.
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Original Russian Text © B.V. Lyalin, K.I. Kashparov, V.A. Petrosyan, 2006, published in Elektrokhimiya, 2006, Vol. 42, No. 7, pp. 890–893.
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Lyalin, B.V., Kashparov, K.I. & Petrosyan, V.A. Electrosynthesis of 3,4-diphenylhexane-3,4-diol by the propiophenone reduction in dimethylformamide. Russ J Electrochem 42, 802–804 (2006). https://doi.org/10.1134/S1023193506070159
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DOI: https://doi.org/10.1134/S1023193506070159