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Phenotypically Unstable Mutations as Markers of Chromosomal Rearrangements Involving DNA Transposons

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Abstract

The review analyzed the validity of using unstable alleles of Drosophila melanogaster genes to assess the rate of movement of mobile genetic elements by the frequency of phenotype change. Several examples show that the instability of alleles with introduced transposons is determined to a greater degree by recombination between them than by the true movement of transposons with the participation of transposase.

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ACKNOWLEDGMENTS

The author thanks I.K. Zakharov for valuable comments.

Funding

The work was supported by the budget project no. 0259-2021-0016.

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  1. Federal Research Center Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, 630090, Novosibirsk, Russia

    L. P. Zakharenko

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Correspondence to L. P. Zakharenko.

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Translated by D. Novikova

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Zakharenko, L.P. Phenotypically Unstable Mutations as Markers of Chromosomal Rearrangements Involving DNA Transposons. Russ J Genet 57, 1253–1257 (2021). https://doi.org/10.1134/S1022795421110156

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