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Russian Journal of Genetics

, Volume 55, Issue 3, pp 396–398 | Cite as

DNA Methylation in Yeast-Like Fungi of the Species Candida albicans Induced by Different Lengths of Exposure to Ozone

  • M. GryzinskaEmail author
  • L. WlazloEmail author
  • B. Nowakowicz-Debek
  • G. Jezewska-Witkowska
  • A. Jakubczak
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Abstract

The objective of the study was to determine global DNA methylation induced by lengths of exposure to ozone in Candida albicans isolates of human and animal origin. The level of global DNA methylation was tested as the relative methylation level in the samples in relation to a methylated control. The analysis revealed differences in the methylation level in the human and animal samples. Ozone had a significant effect on the DNA methylation process, and longer exposure substantially increased the level of total methylated DNA. As expected, the degree of methylation depended on the length of exposure to ozone.

Keywords:

Candida albicans epigenetics global DNA methylation ozone 

Notes

COMPLIANCE WITH ETHICAL STANDARDS

The authors declare that they have no conflict of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.

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Copyright information

© Pleiades Publishing, Inc. 2019

Authors and Affiliations

  1. 1.Faculty of Biology, Animal Sciences and Bioeconomy, Institute of Biological Basis of Animal Production, University of Life Sciences in LublinLublinPoland
  2. 2.Department of Animal Hygiene and Environmental Hazards, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences in LublinLublinPoland

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