Abstract
The genetic diversity of Yersinia pestis strains from the Mongolian natural plague foci has been investigated. A total of 32 strains isolated from western, eastern, and central aimaks, as well as from the territory of the Gobi region, have been studied. Twenty-four strains belong to the main Y. pestis subspecies, while eight belong to non-main subspecies. There is only one strain of biovar medievalis (genovariant 2.MED1) among the strains of the main subspecies, while the rest of the subspecies belong to the biovar antiqua. Biovar antiqua strains are split into three groups. Strains from the eastern part of the country were classified as genovariant 2.ANT3, and those from the western and central regions were classified as genovariant 3.ANT2, which was endemic for Mongolia. One strain from the Bayan-Ulegeiskii aimak had the rare genovariant 4.ANT. None of the strains of the biovar antiqua belonged to its ancient 0.ANT branch, which is inconsistent with the commonly accepted idea that ancient marmot’s plague agent race originates from Mongolia. Six out of eight strains of the non-main subspecies belonged to the ulegeica subspecies, which are endemic to Mongolia, one strain belonged to the microtus group, and the last belonged to a previously uncharacterized variant of the minor subspecies.
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Original Russian Text © L.M. Kukleva, N.Yu. Shavina, G.N. Odinokov, E.G. Oglodin, N.Yu. Nosov, N.A. Vinogradova, N.P. Guseva, G.A. Eroshenko, V.V. Kutyrev, 2015, published in Genetika, 2015, Vol. 51, No. 3, pp. 298–305.
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Kukleva, L.M., Shavina, N.Y., Odinokov, G.N. et al. Analysis of diversity and identification of the genovariants of plague agent strains from Mongolian foci. Russ J Genet 51, 238–244 (2015). https://doi.org/10.1134/S1022795415010068
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DOI: https://doi.org/10.1134/S1022795415010068