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Large-scale genome duplications and paralog divergence in fish

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Abstract

Based on fish genomic studies, we review mechanisms of divergence in duplicated genes (paralogs), resulted in small (“subfunctionalization”) or large (“neofunctionalization”) changes in paralogs. Gene divergence occurs due to several processes, such as non-synonymous substitutions, exon-intron structure rearrangement, and alterations in regulatory regions, which cause differential temporal or spatial expression of paralogous gene copies during ontogenesis.

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  1. Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia

    N. D. Ozernyuk & N. S. Myuge

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  1. N. D. Ozernyuk
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  2. N. S. Myuge
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Original Russian Text © N.D. Ozernyuk, N.S. Myuge, 2013, published in Genetika, 2013, Vol. 49, No. 1, pp. 73–80.

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Ozernyuk, N.D., Myuge, N.S. Large-scale genome duplications and paralog divergence in fish. Russ J Genet 49, 63–69 (2013). https://doi.org/10.1134/S1022795413010080

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  • DOI: https://doi.org/10.1134/S1022795413010080

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