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Effect of polymorphic variants of GH, Pit-1, and β-LG genes on milk production of Holstein cows

  • Animal Genetics
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Abstract

Effect of polymorphic variants of growth hormone (GH), β-lactoglobulin (β-LG), and Pit-1 genes on milk yield was analyzed in a Holstein herd. Genotypes of the cows for these genes were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. Allele frequencies were 0.884 and 0.116 for L and V variants of GH, 0.170 and 0.830 for A and B variants of Pit-1, and 0.529 and 0.471 for A and B variants of β-LG, respectively. GLM procedure of SAS software was used to test the effects of these genes on milk yield. Results indicated significant effects of these genes on milk yield (P < 0.05). Cows with LL genotype of GH produced more milk than cows with LV genotype (P < 0.05). Also, for Pit-1 gene, animals with AB genotype produced more milk than BB genotype (P < 0.05). In the case of β-LG gene, milk yield of animals with AA genotype was more than BB genotype (P < 0.01). Therefore, it might be concluded that homozygote genotypes of GH (LL) and β-LG (AA) were superior compared to heterozygote genotypes, whereas, the heterozygote genotype of Pit-1 gene (AB) was desirable.

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Authors and Affiliations

  1. Department of Animal Sciences, Gorgan University of Agricultural Sciences and Natural Resources, P.O. Box 49189-43464, Gorgan, I.R. Iran

    M. Heidari, M. A. Azari, S. Hasani & S. Zerehdaran

  2. Department of Animal Sciences, Faculty of Agriculture, P.O. Box 163, Gonbad, I.R. Iran

    A. Khanahmadi

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  1. M. Heidari
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Heidari, M., Azari, M.A., Hasani, S. et al. Effect of polymorphic variants of GH, Pit-1, and β-LG genes on milk production of Holstein cows. Russ J Genet 48, 417–421 (2012). https://doi.org/10.1134/S1022795412040060

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