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Analysis of acute ischemic stroke DNA markers in Russian and Moldavian populations

  • Human Genetics
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Abstract

Polymorphisms c.202G > A of prothrombin F2 gene, c.1691G > A of coagulation factor V F5 gene, c.675delinsG of plasminogen activator 1 gene, and (−5)T > C Kozak gene of thrombocytic receptor were studied in the Russian and Moldavian ethnic groups. We have found no association between these polymorphisms and the risk of ischemic stroke development in both ethnic groups. No association was revealed between the risk of stroke development and various combinations of the single nucleotide polymorphisms examined in the sample of ischemic stroke patients from Russia.

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Authors and Affiliations

  1. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia

    E. A. Bondarenko, P. A. Slominsky & S. A. Limborska

  2. Research Institute of Cerebrovascular Pathology and Stroke, Russian State Medical University, Moscow, 117997, Russia

    I. M. Shetova, N. A. Shamalov & V. I. Skvortsova

  3. Institute of Genetics and Plant Physiology, Academy of Science of Moldova, Chisinau, 2002, Moldova

    E. I. Mocan & N. I. Barbacar

  4. Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, 2004, Moldova

    E. I. Mocan, G. S. Kurochkin, S. S. Protopop & L. Lysyi

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  1. E. A. Bondarenko
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  10. S. A. Limborska
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  11. V. I. Skvortsova
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Correspondence to E. A. Bondarenko.

Additional information

Original Russian Text © E.A. Bondarenko, I.M. Shetova, N.A. Shamalov, E.I. Mocan, N.I. Barbacar, G.S. Kurochkin, S.S. Protopop, L., Lysyi, P.A. Slominsky, S.A. Limborska, V.I. Skvortsova, 2011, published in Genetika, 2011, Vol. 47, No.10, pp. 1393–1401.

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Bondarenko, E.A., Shetova, I.M., Shamalov, N.A. et al. Analysis of acute ischemic stroke DNA markers in Russian and Moldavian populations. Russ J Genet 47, 1240–1247 (2011). https://doi.org/10.1134/S1022795411100048

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  • DOI: https://doi.org/10.1134/S1022795411100048

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