Skip to main content
Log in

The role of natural selection in the evolution of mitochondrial haplogroups in Northeastern Eurasia

  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

The role of natural selection in the evolution of the mitochondrial genome in human populations from Northeastern Eurasia was studied. Selection for the regions-specific haplogroup C was demonstrated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Wallace, D.C., Brown, M.D., and Lott, M.T., Mitochondrial DNA Variation in Human Evolution and Disease, Gene, 1999, vol. 238, pp. 211–230.

    Article  CAS  PubMed  Google Scholar 

  2. Starikovskaya, Y.B., Sukernik, R.I., Schurr, T.G., et al., mtDNA Diversity in Chukchi and Siberian Eskimos: Implications for the Genetic History of Ancient Beringia and the Peopling of the New World, Am. J. Hum. Genet., 1998, vol. 63, pp. 1473–1491.

    Article  CAS  PubMed  Google Scholar 

  3. Derbeneva, O.A., Sukernik, R.I., Volodko, N.V., et al., Analysis of Mitochondrial DNA Diversity in the Aleuts of the Commander Islands and Its Implications for the Genetic History of Beringia, Am. J. Hum. Genet., 2002, vol. 71, pp. 415–421.

    Article  CAS  PubMed  Google Scholar 

  4. Starikovskaya, E.B., Sukernik, R.I., Derbeneva, O.A., et al., Mitochondrial DNA Diversity in Indigenous Populations of the Southern Extent of Siberia, and the Origins of Native American Haplogroups, Ann. Hum. Genet., 2005, vol. 69, pp. 67–89.

    Article  CAS  PubMed  Google Scholar 

  5. Derenko, M., Malyarchuk, B., Grzybowski, T., et al., Phylogeographic Analysis of Mitochondrial DNA in Northern Asian Populations, Am. J. Hum. Genet., 2007, vol. 81, pp. 1025–1041.

    Article  CAS  PubMed  Google Scholar 

  6. Volodko, N.V., Starikovskaya, Y.B., Mazunin, I.O., et al., Mitochondrial Genome Diversity in Arctic Siberians, with private Reference to the Evolutionary History of Beringia and Pleistocenic Peopling of the Americas, Am. J. Hum. Genet., 2008, vol. 82, pp. 1084–1100.

    Article  CAS  PubMed  Google Scholar 

  7. Harpending, H.C., Batzer, M.A., and Gurven, M., et al. Genetic Traces of Ancient Demography, Proc. Natl. Acad. Sci. USA, 1998, vol. 95, pp. 1961–1967.

    Article  CAS  PubMed  Google Scholar 

  8. Mishmar, D., Ruiz-Pesini, E., Golik, P., et al., Natural Selection Shaped Regional mtDNA Variation in Humans, Proc. Natl. Acad. Sci. USA, 2003, vol. 100, pp. 171–176.

    Article  CAS  PubMed  Google Scholar 

  9. Ruiz-Pesini, E., Mishmar, D., Brandon, M., et al., Effects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA, Science, 2004, vol. 303, pp. 223–226.

    Article  CAS  PubMed  Google Scholar 

  10. Elson, J.L., Turnbull, D.M., and Howell, N., Comparative Genomics and the Evolution of Human Mitochondrial DNA: Assessing the Effects of Selection, Am. J. Hum. Genet., 2004, vol. 74, pp. 229–238.

    Article  CAS  PubMed  Google Scholar 

  11. Kivisild, T., Shen, P., Wall, D.P., et al., The Role of Selection in the Evolution of Human Mitochondrial Genomes, Genetics, 2006, vol. 172, pp. 373–387.

    Article  CAS  PubMed  Google Scholar 

  12. Ingman, M. and Gyllensten, U., Rate Variation between Mitochondrial Domains and Adaptive Evolution in Humans, Hum. Mol. Genet., 2007, vol. 16, pp. 2281–2287.

    Article  CAS  PubMed  Google Scholar 

  13. Sun, C., Kong, Q.P., and Zhang, Y.P., The Role of Climate in Human Mitochondrial DNA Evolution: A Reappraisal, Genomics, 2007, vol. 89, pp. 338–342.

    Article  CAS  PubMed  Google Scholar 

  14. Tamm, E., Kivisild, T., Reidla, M., et al., Beringian Standstill and Spread of Native American Founders, PLoS ONE, 2007, vol. 2, no. 9, p. e829.

    Article  PubMed  Google Scholar 

  15. Rand, D.M. and Kann, L.M., Excess Amino Acid Polymorphism in Mitochondrial DNA: Contrasts among Genes from Drosophila, Mice, and Humans, Mol. Biol. Evol., 1996, vol. 13, pp. 735–748.

    CAS  PubMed  Google Scholar 

  16. Skulachev, V.P., Oxygen in the Living Cell: Good and Evil, Sorosovskii Obrazovatel’nyi Zh., 1996, vol. 3, pp. 4–10.

    Google Scholar 

  17. Brand, M.D., Chien, L.F., Ainscow, E.K., et al., The Causes and Functions of Mitochondrial Proton Leak, Biochim. Biophys. Acta, 1994, vol. 1187, pp. 132–139.

    Article  CAS  PubMed  Google Scholar 

  18. Rolfe, D.F. and Brand, M.D., The Physiological Significance of Mitochondrial Proton Leak in Animal Cells and Tissues, Biosci. Rep., 1997, vol. 17, pp. 9–16.

    Article  CAS  PubMed  Google Scholar 

  19. Leonard, W.R., Snodgrass, J.J., and Sorensen, M.V., Metabolic Adaptations in Indigenous Siberian Populations, Annu. Rev. Anthropol., 2005, vol. 34, pp. 451–471.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to N. P. Eltsov.

Additional information

Original Russian Text © N.P. Eltsov, N.V. Volodko, E.B. Starikovskaya, I.O. Mazunin, R.I. Sukernik, 2010, published in Genetika, 2010, Vol. 46, No. 9, pp. 1247–1249.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Eltsov, N.P., Volodko, N.V., Starikovskaya, E.B. et al. The role of natural selection in the evolution of mitochondrial haplogroups in Northeastern Eurasia. Russ J Genet 46, 1105–1107 (2010). https://doi.org/10.1134/S1022795410090243

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1022795410090243

Keywords

Navigation