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Small nucleolar RNAs and their genes in vertebrates

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Abstract

Genes of box C/D small nucleolar RNAs (snoRNAs) were searched for in the genomes of members of all classes of vertebrates that do not belong to placental mammals. A tendency for an increase in the number of copies of snoRNA genes was observed in such vertebrates. This trend was most pronounced in anamnia (amphibians and fish). Box C mutations were found in 14 snoRNAs in all gene copies among all species studied. The role of the described events is discussed.

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References

  1. Maden, B.E., The Numerous Modified Nucleotides in Eukaryotic Ribosomal RNA, Prog. Nucleic Acid Res. Mol. Biol., 1990, vol. 39, pp. 241–303.

    Article  CAS  PubMed  Google Scholar 

  2. Kiss-Laszlo, Z., Henry, Y., Bachellerie, J.P., et al., Site-Specific Ribose Methylation of Preribosomal RNA: A Novel Function for Small Nucleolar RNAs, Cell, 1996, vol. 85, pp. 1077–1088.

    Article  CAS  PubMed  Google Scholar 

  3. Decatur, W.A. and Fournier, M.J., rRNA Modifications and Ribosome Function, Trends Biochem. Sci., 2002, vol. 27, pp. 344–351.

    Article  CAS  PubMed  Google Scholar 

  4. Makarova, Yu.A. and Kramerov, D.A., Small Nucleolar RNA Genes, Russ. J. Genet., 2007, vol. 43, no. 2, pp. 149–158.

    Article  Google Scholar 

  5. Makarova, J.A. and Kramerov, D.A., Analysis of C/D Box snoRNA Genes in Vertebrates: The Number of Copies Decreases in Placental Mammals, Genomics, 2009, vol. 94, pp. 11–19.

    Article  CAS  PubMed  Google Scholar 

  6. Lestrade, L. and Weber, M.J., snoRNA-LBME-db, a Comprehensive Database of Human H/ACA and C/D Box snoRNAs, Nucl. Acids Res., 2006, vol. 34, pp. 158–162.

    Article  Google Scholar 

  7. Gregory, T.R., Nicol, J.A., Tamm, H., et al., Eukaryotic Genome Size Databases, Nucl. Acids Res., 2007, vol. 35, pp. 332–338.

    Article  Google Scholar 

  8. Watkins, N.J., Dickmanns, A., and Luhrmann, R., Conserved Stem II of the Box C/D Motif Is Essential for Nucleolar Localization and Is Required, along with the 15.5K Protein, for the Hierarchical Assembly of the Box C/D snoRNA, Mol. Cell. Biol., 2002, vol. 22, pp. 8342–8352.

    Article  CAS  PubMed  Google Scholar 

  9. Esguerra, J., Warringer, J., and Blomberg, A., Functional Importance of Individual rRNA 2′-O-Ribose Methylations Revealed by High-Resolution Phenotyping, RNA, 2008, vol. 14, pp. 649–656.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia

    J. A. Makarova & D. A. Kramerov

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  1. J. A. Makarova
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  2. D. A. Kramerov
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Correspondence to D. A. Kramerov.

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Original Russian Text © J.A. Makarova, D.A. Kramerov, 2010, published in Genetika, 2010, Vol. 46, No. 9, pp. 1185–1187.

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Makarova, J.A., Kramerov, D.A. Small nucleolar RNAs and their genes in vertebrates. Russ J Genet 46, 1052–1054 (2010). https://doi.org/10.1134/S1022795410090097

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  • DOI: https://doi.org/10.1134/S1022795410090097

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