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Proteolytic control of expression of Vibrio fischeri lux-operon genes in Escherichia coli cells

  • Genetics of Microorganisms
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Abstract

The key elements of the regulatory system activating expression of the lux-operon genes in the marine bacteria Vibrio fischeri are the LuxR protein (an activator of transcription) and N-(3-oxohexanoyl) L-homoserine lactone (an autoinducer, AI). It is shown that the ATP-dependent proteases ClpXP and Lon take part in the negative control of expression of the lux-operon genes and that AI protects the LuxR protein from proteolysis.

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Authors and Affiliations

  1. State Reseatch Institute of Genetics and Selection of Industrial Microorganisms, Moscow, 117545, Russia

    O. E. Mel’kina, I. V. Manukhov & G. B. Zavilgelsky

Authors
  1. O. E. Mel’kina
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  2. I. V. Manukhov
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  3. G. B. Zavilgelsky
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Corresponding author

Correspondence to G. B. Zavilgelsky.

Additional information

Original Russian Text © O.E. Mel’kina, I.V. Manukhov, G.B. Zavilgelsky, 2010, published in Genetika, 2010, Vol. 46, No. 8, pp. 1050–1056.

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Mel’kina, O.E., Manukhov, I.V. & Zavilgelsky, G.B. Proteolytic control of expression of Vibrio fischeri lux-operon genes in Escherichia coli cells. Russ J Genet 46, 932–937 (2010). https://doi.org/10.1134/S1022795410080041

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  • DOI: https://doi.org/10.1134/S1022795410080041

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