Skip to main content
Log in

Effects of monorecessive and double recessive mutations affecting coat color on the monoamine content of the brain of the American mink (Mustela vison Schreber, 1777)

  • Animal Genetics
  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

The effects of mutations affecting the coat color on the dopamine, noradrenaline, and serotonin contents of the hypothalamus and brainstem of the American mink have been studied. The sample comprised standard (+/+) and mutant minks, including the monorecessive pastel (b/b), silver-blue (p/p), and white hedlund (h/h) and the combination double recessive sapphire (a/a p/p) and pearl (k/k p/p) ones. The dopamine content of the brainstem of the monorecessive pastel (b/b) and silver-blue (p/p) minks has been found to be higher than in standard (+/+) minks. Conversely, the homozigosity for two coat color loci in double recessive pearl minks (k/k p/p) significantly decreases the noradrenaline and serotonin contents of the hypothalamus. In addition, monorecessive and double recessive minks differ from each other in the serotonin contents of the midbrain and medulla.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Il’ina, E.D. and Kuznetsov, G.A., Osnovy genetiki i selektsii pushnykh zverei (Principles of Fur Animal Genetics and Breeding), Moscow: Kolos, 1983.

    Google Scholar 

  2. Nes, N., Einarsson, E., Lohi, O., Jarosz, S., and Sheelje, R., Beautiful Fur Animals and Their Colour Genetics, Glostrup: Scientifur, 1988.

    Google Scholar 

  3. Trapezov, O.V., Black Crystal: A Novel Coat Color Mutant in the American Mink, J. Hered., 1997, vol. 88, pp. 164–166.

    CAS  PubMed  Google Scholar 

  4. Koldaeva, E.M., Genetika i selektsiya (kniga pervaya) (Genetics and Breeding: Book 1), Moscow: Izvestiya, 2004.

    Google Scholar 

  5. Popova, N.K., Voitenko, N.N., Kulikov, A.V., et al., The Pleiotropic Effect of One-Locus (p/p) and Two-Locus (a/a p/p) Mutations of Mink Coat Color Genes on Serotonin Metabolism in the Brain, Russ. J. Genet., 1994, vol. 30, no. 11, pp. 1513–1515.

    CAS  Google Scholar 

  6. Popova, N.K., Nikulina, E.M., Voitenko, N.N., et al., The One-Locus Silver-Blue Fur Color Mutation (p/p) in Minks Affects the Dopamine System of the Brain, Russ. J. Genet., 1996, vol. 32, no. 3, pp. 452–454.

    CAS  Google Scholar 

  7. Voitenko, N.N. and Trapezov, O.V., Effect of Four Coat Color Mutations (SR, S, SH, and h) on Brain Monoamine Oxidase in Mink, Russ. J. Genet., 2001, vol. 37, no. 4, pp. 519–522.

    Article  CAS  Google Scholar 

  8. Trapezov, O.V., Trapezova, L.I., and Sergeev, E.G., Effect of Coat Color Gene on the Behavioral Polymorphism in the Ranch-Bred American Mink (Mustela vison Schreber, 1777) and Sable (Martes zibellina Linnaeus, 1758), Russ. J. Genet., 2007, vol. 37, no. 4, pp. 519–522.

    Google Scholar 

  9. Felten, D.L. and Sladek, J.R., Monoamine Distribution in Primate Brain: V. Monoaminergic Nuclei: Anatomy, Pathways and Local Organization, Brain Res. Bull., 1983, vol. 58, no. 2, pp. 171–284.

    Article  Google Scholar 

  10. Smith, S.E., Whitaker, C.H., Davis, L.F., and Nobel, P.V., The Inheritance of Three Coat Color Mutations in Ranch-Raised Mink, J. Hered., 1941, vol. 32, pp. 173–176.

    Google Scholar 

  11. Shackelford, R.M. and Cole, L.J., Screw-Neck in the Pastel Color Phase of Ranch-Bred Mink, J. Hered., 1947, vol. 38, pp. 203–209.

    Google Scholar 

  12. Shackelford, R.M., The Nature of Coat Colour Difference in Mink and Foxes, Genetics, 1948, vol. 33, pp. 311–336.

    Google Scholar 

  13. Shackelford, R.M. and Moore, W.L., Genetics Basis of Some White Phenotypes in the Ranch Mink, J. Hered., 1954, vol. 45, pp. 173–176.

    Google Scholar 

  14. Schlumpf, M., Lichensteiger, W., Langemann, H., et al., A Fluorometric Microtechnique for Simultaneous Assay of 5-Hydroxytryptamine, Noradrenaline and Dopamine in Milligrams of Brain Tissue, Biochem. Pharmacol., 1974, vol. 23, no. 6, pp. 2337–2346.

    Article  CAS  PubMed  Google Scholar 

  15. Trut, L.N., The Problem of Destabilizing Selection in Development, in Sovremennye kontseptsii evolyutsionnoi genetiki (Modern Concepts of Evolutionary Genetics), Novosibirsk, 2000, pp. 7–21.

  16. Klochkov, D.V., Alekhina, T.A., Trapezov, O.V., and Petrenko, O.I., Estrus Circle, Folliculogenesis, Catecholamines after Horionic Gonadotropin Stimulation in Mink Selected for Behavior, Zh. Evol. Biokhim. Fiziol., 2005, vol. 41, no. 3, pp. 266–271.

    CAS  PubMed  Google Scholar 

  17. Szot, P., Weinshenker, D., and White, S.S., Norepinephrine-Deficient Mice Have Increased Susceptibility to Seizure-Induced Stimuli, J. Neurosci., 1999, vol. 19, no. 24, pp. 10985–10992.

    CAS  PubMed  Google Scholar 

  18. Alekhina, T.A., Prokudina, O.I., and Ryazanova, M.A., Typological Patterns of Behavior in Rats Selected for Elevating and Reducing of Pathological Moving, Linkage with Monoamines of Brain, Pavlov J. Higher Nerv. Act., 2007, vol. 57, no. 3, pp. 336–343.

    Google Scholar 

  19. Keeler, C.E., Coat Color, Physique, and Temperament, J. Heredity, 1947, vol. 9, pp. 271–277.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to O. V. Trapezov.

Additional information

Original Russian Text © O.V. Trapezov, L.I. Trapezova, T.A. Alekhina, D.V. Klochkov, Yu.N. Ivanov, 2009, published in Genetika, 2009, Vol. 45, No. 12, pp. 1641–1645.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Trapezov, O.V., Trapezova, L.I., Alekhina, T.A. et al. Effects of monorecessive and double recessive mutations affecting coat color on the monoamine content of the brain of the American mink (Mustela vison Schreber, 1777). Russ J Genet 45, 1450–1453 (2009). https://doi.org/10.1134/S1022795409120072

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1022795409120072

Keywords

Navigation