Skip to main content
SpringerLink
Log in

Microsatellite DNA variability in the populations of muskoxen Ovibos moschatus transplanted into the Russian North

  • Animal Genetics
  • Published:
Russian Journal of Genetics Aims and scope Submit manuscript

Abstract

The muskoxen populations introduced to the Taimyr Peninsula and Wrangel Island in 1974 to 1975 were examined for sequence variation at seven microsatellite loci. Donor material originated from the populations of Banks Island (Canada) and Eastern Greenland. Relative to the allele frequencies, both introduced populations demonstrated rather strong deviation from the populations of the native range. At the same time, population allelic structures evidenced that they were closer to the Greenland populations. Estimates of genetic diversity at microsatellite loci (expected heterozygosity and the allele number) in the introduced muskoxen were found to be high for populations originating from a small number of founder individuals. In the immigrants, linkage disequilibrium and deviation of the genotype frequencies from the Hardy-Weinberg proportions were observed, which was mainly caused by the deficit of heterozygotes. The same pattern was also typical of native populations and was explained in terms of specific population structure and demographic processes. The latter were manifested as a periodic decline of the effective population size, resulting in the prevailing influence of genetic drift and inbreeding. The consequences of genetic drift were not as dramatic, as could be expected, which may be explained by a high mutation rate of neutral microsatellite loci and fast growth of the new populations.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Vereshchagin, N.K. and Baryshnikov, G.F., Mammal Extinction in the Quaternary Period of Northern Eurasia, in Mlekopitayushchie Severnoi Evrazii v chetvertichnom periode (Quaternary Mammal Fauna of Northern Eurasia), Leningrad: Zool. Inst. Akad. Nauk SSSR, 1985, pp. 3–38.

    Google Scholar 

  2. Gruzdev, A.R. and Sipko, T.P., Productivity and Demography of Muskoxen on Wrangel Island, J. Rangifer Rep., 2003, no. 11, p. 30.

  3. Sipko, T.P., Gruzdev, A.R., and Babashkin, K.N., Demography and Productivity of Muskoxen in Taymir, Rangifer, 2003, no. 7, p. 40.

  4. Fleischman, C.L., Genetic Variation in Muskoxen (Ovibos moschatus), MSc Thesis, Fairbanks: Univ. Alaska, 1986.

    Google Scholar 

  5. Engel, S.R., Linn, R.A., Taylor, J.F., and Davis, S., Conservation of Microsatellite Loci across Species of Artiodactyls: Implications for Population Studies, J. Mammal., 1996, vol. 77, pp. 504–518.

    Article  Google Scholar 

  6. Groves, P., Intraspecific Variation of Mitochondrial DNA of Muskoxen, Based on Control-Region Sequences, Can. J. Zool., 1997, vol. 75, pp. 568–575.

    Article  CAS  Google Scholar 

  7. Groves, P. and Shields, G.F., Cytochrome B Sequences Suggest Convergent Evolution of the Asian Takin and Arctic Muskox, Mol. Phylogenet. Evol., 1997, vol. 8, pp. 363–374.

    Article  PubMed  CAS  Google Scholar 

  8. Holm, L.-E., Forchhammer, M.C., and Boomsma, J.J., Low Genetic Variation in Muskoxen (Ovibos moschatus) from Western Greenland Using Microsatellites, Mol. Ecol., 1999, vol. 8, pp. 675–679.

    Article  PubMed  CAS  Google Scholar 

  9. Van Coeverden de Groot, P.J., Conservation Genetic Implications of Microsatellite Variation in the Muskox Ovibos moschatus: The Effect of Refugial Isolation and the Arctic Ocean on Genetic Structure, Dis. Abstracts Int., 2002, vol. 62, no. 4, p. 1763.

    Google Scholar 

  10. Van Coeverden, P.J. and Boag, P., Optimization of Novel Polymorphic Microsatellites in Muskox (Ovibos moschatus) Leads to an Increased Estimate of Microsatellite Diversity, Mol. Ecol. Notes, 2004, vol. 4, pp. 713–715.

    Article  CAS  Google Scholar 

  11. Frankham, R., Ballou, J.D., and Briscoe, D.A., Introduction to Conservation Genetics, Cambridge: Cambridge Univ. Press, 2002.

    Google Scholar 

  12. Dallas, J.F., Estimation of Microsatellite Mutation Rates in Recombinant Inbred Strains of Mouse, Mamm. Genome, 1992, vol. 5, pp. 32–38.

    Google Scholar 

  13. Weber, J.L. and Wong, C., Mutation of Human Short Tandem Repeats, Hum. Mol. Genet., 1993, vol. 2, pp. 1123–1128.

    Article  PubMed  CAS  Google Scholar 

  14. Goldstein, D.B. and Schlotterer, C., Microsatellites: Evolution and Applications, Oxford: Oxford Univ. Press, 1999.

    Google Scholar 

  15. Olesen, C.R., Rapid Population Increase in an Introduced Muskox Population, West Greenland, Rangifer, 1993, vol. 13, no. 1, pp. 27–32.

    Google Scholar 

  16. Sambrook, J., Fritsch, E.F., and Maniatis, T., Molecular Cloning: A Laboratory Manual, New York: Cold Spring Harbor Lab. Press, 1989.

    Google Scholar 

  17. Wilson, G.A., Strobeck, C., Wu, L., and Coffin, J.W., Characterization of Microsatellite Loci in Caribou (Rangifer tarandus), and Their Use in Other Arctiodactyls, Mol. Ecol., 1997, vol. 6, pp. 697–699.

    Article  PubMed  CAS  Google Scholar 

  18. Nei, M., Molecular Evolutionary Genetics, New York: Columbia Univ., 1987.

    Google Scholar 

  19. Goudet, J., FSTAT, a Program to Estimate and Test Gene Diversities and Fixation Indices: Version 2.9.3.2, 2001, http://www.unil.ch/izea/softwares/fstat.html

  20. Goldstein, D.B. and Pollock, D.D., Launching Microsatellites: A Review of Mutation Processes and Methods of Phylogenetic Inference, J. Hered., 1997, vol. 88, pp. 335–342.

    PubMed  CAS  Google Scholar 

  21. Raymond, M. and Rousset, F., GENEPOP (3.4): Population Genetics Software for Exact Tests and Ecumenicism, J. Heredity, 1995, vol. 86, pp. 248–249.

    Google Scholar 

  22. Rice, W.R., Analysing Tables of Statistical Tests, Evolution, 1989, vol. 43, pp. 223–225.

    Article  Google Scholar 

  23. Weir, B.S. and Cockerham, C.C., Estimating F-Statistics for the Analysis of Population Structure, Evolution, 1984, vol. 38, pp. 117–125.

    Article  Google Scholar 

  24. Rousset, F., Equilibrium Values of Measures of Population Subdivision for Stepwise Mutation Processes, Genetics, 1996, vol. 142, pp. 1357–1362.

    PubMed  CAS  Google Scholar 

  25. Dieringer, D. and Schlotterer, C., Microsatellite Analyser (MSA): A Platform Independent Analysis Tool for Large Microsatellite Data Sets, Mol. Ecol. Notes, 2003, vol. 3, no. 1, pp. 167–169.

    Article  CAS  Google Scholar 

  26. Felsenstein, J., PHYLIP (Phylogeny Inference Package): Version 35c, Seattle, Washington: Univ. Washington, 1993.

    Google Scholar 

  27. Page, R.D.M., TREEVIEW: An Application to Display Phylogenetic Trees on Personal Computers, Computer Appl. Biosci., 1996, vol. 12, pp. 357–358.

    CAS  Google Scholar 

  28. Hedrick, P.W., Genetics of Populations, Boston: Jones and Bartlett, 2000, 2nd ed.

    Google Scholar 

  29. Lent, P.C., Muskox Management Controversies in North America, Biol. Conserv., 1971, vol. 3, no. 4, pp. 255–263.

    Article  Google Scholar 

  30. Kimura, M. and Crow, J.F., The Number of Alleles that Can Be Maintained in a Finite Population, Genetics, 1964, vol. 49, pp. 725–738.

    PubMed  CAS  Google Scholar 

  31. Brinkmann, B., Klintschar, M., Neuhuber, F., et al., Mutation Rate in Human Microsatellites: Influence of the Structure and Length of the Tandem Repeat, Am. J. Hum. Genet., 1998, vol. 62, pp. 1408–1415.

    Article  PubMed  CAS  Google Scholar 

  32. Ellegren, H., Heterogeneous Mutation Processes in Human Microsatellite DNA Sequences, Nat. Genet., 2000, vol. 24, pp. 400–402.

    Article  PubMed  CAS  Google Scholar 

  33. Schlotterer, C., Ritter, R., Harr, B., and Brem, G., High Mutation Rate of a Long Microsatellite Allele in Drosophila melanogaster Provides Evidence for Allele-Specific Mutation Rates, Mol. Biol., 1998, vol. 15, pp. 1269–1274.

    CAS  Google Scholar 

  34. Ohta, T. and Kimura, M., The Model of Mutation Appropriate to Estimate the Number of Electrophoretically Detectable Alleles in a Genetic Population, Genet. Res., 1973, vol. 22, pp. 201–204.

    Article  Google Scholar 

  35. Yakushkin, G.D., Ovtsebyki na Taimyre (Muskox in Taimyr), Novosibirsk: NIIS-kh. Krainego Severa Russ. Akad. S-kh. Nauk SO, 1998.

    Google Scholar 

  36. Spencer, D.L. and Lensink, C.J., The Muskox of Nunivak Island, Alaska, J. Wildlife Manag., 1970, vol. 34, no. 1, pp. 1–15.

    Article  Google Scholar 

  37. Thing, H., Henrichsen, P., and Lassen, P., Status of the Muskox in Greenland, Biol. Pap. Univ. Alaska Spec. Rep., 1984, vol. 4, pp. 1–6.

    Google Scholar 

  38. Gunn, A., Shank, C., and McLean, B., The History, Status and Management of Muskoxen on Banks Island, Arctic, 1991, vol. 44, no. 3, pp. 188–195.

    Google Scholar 

  39. Larter, N.C. and Nagy, J.A., Calf Production, Calf Survival, and Recruitment of Muskoxen on Banks Island during a Period of Changing Population Density from 1986–99, Arctic, 2001, vol. 54, no. 4, pp. 394–406.

    Google Scholar 

  40. MacPhee, R., Tikhonov, A., Mol, D., and Greenwood, A.D., Late Quaternary Loss of Genetic Diversity in Muskox (Ovibos), BMC Evol. Biol., 2005, vol. 5, p. 49.

    Article  PubMed  CAS  Google Scholar 

  41. Barr, W., Back from the Brink, Calgary: Arctic Inst. North America, 1991.

    Google Scholar 

  42. Forchhammer, M. and Boertmann, D., The Muskoxen Ovibos moschatus in the North and Northeast Greenland: Population Trends and Influence of Abiotic Parameters on Population Dynamics, Ecogeography, 1993, vol. 16, pp. 299–308.

    Article  Google Scholar 

  43. Hedrick, P.W., Purging Inbreeding Depression and the Probability of Extinction: Full-Sib Mating, Herediry, 1994, vol. 73, pp. 363–372.

    Article  Google Scholar 

  44. Laikre, L., Andren, R., Larsson, H.O., and Ryman, N., Inbreeding Depression in Brown Bear, Ursus arctos, Biol. Conserv., 1996, vol. 76, pp. 69–72.

    Article  Google Scholar 

  45. Gunn, A., Differences in the Sex and Age Composition of Two Muskox Populations and Implications for Male Breeding Strategies, Rangifer, 1992, vol. 12, no. 1, pp. 17–19.

    Google Scholar 

  46. Gruzdev, A.R. and Sipko, T.P., Vrangel Island Muskox (Ovibos mosshatus Zimermann, 1780) Populations State of the Art, in Priroda ostrova Vrangelya: sovremennye issledovaniya (Vrangel Island Nature: Current Research), Collection of Scientific Papers, St. Petersburg: Asterion, 2007.

    Google Scholar 

  47. Altukhov, Yu.P., Geneticheskie protsessy v populyatsiyakh (Genetic Processes in Populations), Moscow: Akademkniga, 2003.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia

    N. V. Gordeeva

  2. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, 119071, Russia

    T. P. Sipko

  3. Wrangel Island State Reserve, Pevek, 689400, Russia

    A. P. Gruzdev

Authors
  1. N. V. Gordeeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. P. Sipko
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. P. Gruzdev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. V. Gordeeva.

Additional information

Original Russian Text © N.V. Gordeeva, T.P. Sipko, A.P. Gruzdev, 2009, published in Genetika, 2009, Vol. 45, No. 7, pp. 932–940.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gordeeva, N.V., Sipko, T.P. & Gruzdev, A.P. Microsatellite DNA variability in the populations of muskoxen Ovibos moschatus transplanted into the Russian North. Russ J Genet 45, 817–825 (2009). https://doi.org/10.1134/S1022795409070096

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S1022795409070096

Keywords

Search

Navigation