Abstract
Insulators are regulatory elements having two properties. First, they are able to disturb the interaction between promoters and enhancers/silencers. Second, they are able to block distribution of the heterochromatin. The best-studied are the Su(Hw)-dependent insulators of Drosophila melanogaster, activity of which is determined by the Su(Hw) protein. In this study it was demonstrated that novel, evolutionary conservative transcription factor E(y)2/Sus1 interacted with the Su(Hw) zinc-finger domain and was present in the protein complex, associated with the Su(Hw)-dependent insulators.
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Original Russian Text © M.M. Kurshakova, D.V. Kopytova, E.N. Nabirochkina, N.V. Soshnikova, S.G. Georgieva, A.N. Krasnov, 2009, published in Genetika, 2009, Vol. 45, No. 3, pp. 330–335.
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Kurshakova, M.M., Kopytova, D.V., Nabirochkina, E.N. et al. Conservative E(y)2/Sus1 protein interacts with the Su(Hw)-dependent insulators in Drosophila . Russ J Genet 45, 287–291 (2009). https://doi.org/10.1134/S1022795409030041
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DOI: https://doi.org/10.1134/S1022795409030041