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Effect of the apterous 56f mutation on N-acetyltransferase and alkaline phosphatase activities in Drosophila melanogaster females

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Abstract

Alkaline phosphatase (AP) and N-acetyltransferase (NAT) activities were studied in 1-day-old Drosophila melanogaster females of the apterous 56f (ap 56f) strain, having an decreased level of the juvenile hormone (JH) and a increased level of dopamine as a result of the mutation, and in the Canton S ancestral wild-type strain in the normal conditions and upon an experimental increase in JH titer. The AP and NAT activities in ap 56f females were significantly lower than in Canton S females in the norm. JH application increased the AP activity of mutant females to the level characteristic to JH-treated wild-type females.

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References

  1. Bourgouin, C., Lundgren, S.E., and Thomas, J.B., Apterous Is a Drosophila LIM Domain Gene Required for the Development of a Subset of Embryonic Muscles, Neuron, 1992, vol. 9, pp. 549–561.

    Article  PubMed  CAS  Google Scholar 

  2. Cohen, B., McGuffin, E., Pfeifle, C., et al., Apterous: A Gene Required for Imaginal Disc Development in Drosophila Encodes a Member of the LIM Family of Developmental Regulatory Proteins, Genes Dev., 1992, vol. 6, pp. 715–729.

    Article  PubMed  CAS  Google Scholar 

  3. Wilson, T.G., A Mosaic Analysis of the apterous Mutation in Drosophila melanogaster, Dev. Biol., 1981, vol. 85, pp. 434–445.

    Article  PubMed  CAS  Google Scholar 

  4. Wilson, T.G., Expression of Phenotypes in a Temperature-Sensitive Allele of the apterous Mutation in Drosophila melanogaster, Dev. Biol., 1981, vol. 85, pp. 425–433.

    Article  PubMed  CAS  Google Scholar 

  5. Gavin, J.A. and Williamson, J.H., Juvenile Hormone-Induced Vitellogenesis in apterous-4, a Non-Vitellogenic Mutant in Drosophila melanogaster, J. Insect Physiol., 1976, vol. 22, pp. 1737–1742.

    Article  PubMed  CAS  Google Scholar 

  6. Ringo, J., Werczberger, R., Altaratz, M., and Segal, D., Female Sexual Receptivity and Juvenile Hormone Synthesis Are Defective in Mutants of the apterous Gene of Drosophila melanogaster, Behav. Genet., 1991, vol. 21, pp. 453–469.

    Article  PubMed  CAS  Google Scholar 

  7. Ringo, J., Werczberger, R., and Segal, D., Male Sexual Signaling Is Defective in Mutants of the apterous Gene of Drosophila melanogaster, Behav. Genet., 1992, vol. 22, pp. 469–487.

    Article  PubMed  CAS  Google Scholar 

  8. Altaratz, M., Applebaum, Sh.W., Richard, D.S., et al., Regulation of Juvenile Hormone Synthesis in Wild-Type and apterous Mutant Drosophila, Mol. Cell. Endocrinol., 1991, vol. 81, pp. 205–216.

    Article  PubMed  CAS  Google Scholar 

  9. Gruntenko, N.E., Chentsova N.A., Andreenkova, E.V., et al., Stress Response in a Juvenile Hormone Deficient Drosophila melanogaster Mutant apterous 56f, Insect Mol. Biol., 2003, vol. 12, pp. 353–363.

    Article  PubMed  CAS  Google Scholar 

  10. Wright, T.R.F., Genetics of Biogenic Amines Metabolism, Sclerotization and Melanization in Drosophila melanogaster, Adv. Genet., 1987, vol. 24, pp. 127–221.

    Article  PubMed  CAS  Google Scholar 

  11. Sukhanova, M.Jh., Grenback, L.G., Gruntenko, N.E., et al. Alkaline Phosphatase in Drosophila under Heat Stress, J. Insect Physiol., 1996, vol. 42, pp. 161–165.

    Article  CAS  Google Scholar 

  12. Rauschenbach, I.Y., Sukhanova, M.Z., Shumnaya, L.V., et al., Role of Dopa Decarboxylase and N-Acetyltransferase in Regulation of Dopamine Content in Drosophila virilis under Normal and Heat Stress Conditions, Insect Biochem. Mol. Biol., 1997, vol. 27, pp. 729–734.

    Article  PubMed  CAS  Google Scholar 

  13. Gruntenko, N.E., Chentsova, N.A., Andreenkova, E.V., et al., The Effect of Mutations Altering Biogenic Amine Metabolism in Drosophila on Viability and the Response to Heat Stress, Arch. Insect Biochem. Physiol., 2004, vol. 55, pp. 55–67.

    Article  PubMed  CAS  Google Scholar 

  14. Adon’eva, N.V., Alekseev, A.A., Gruntenko, N.E., and Raushenbakh, I.Yu., Juvenile Hormone and 20-Hydroxyecdysone Regulate the Activity of N-Acetyltransferase in Drosophila virilis, Dokl. Akad. Nauk, 2007, vol. 416, no. 2, pp. 261–263.

    Google Scholar 

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Correspondence to I. Yu. Rauschenbach.

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Original Russian Text © E.V. Bogomolova, N.V. Adonyeva, N.E. Gruntenko, I.Yu. Rauschenbach, 2008, published in Genetika, 2008, Vol. 44, No. 5, pp. 710–712.

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Bogomolova, E.V., Adonyeva, N.V., Gruntenko, N.E. et al. Effect of the apterous 56f mutation on N-acetyltransferase and alkaline phosphatase activities in Drosophila melanogaster females. Russ J Genet 44, 617–619 (2008). https://doi.org/10.1134/S1022795408050153

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  • DOI: https://doi.org/10.1134/S1022795408050153

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