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Genetic diversity of the house mouse Mus musculus and geographic distribution of its subspecies-specific RAPD markers on the territory of Russia

  • Animal Genetics
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Abstract

Genetic diversity and geographic distribution of taxon-specific RAPD markers was examined in ten local populations of the house mouse Mus musculus (n = 42). The house mice were generally characterized by moderate genetic variation: polymorphism P 99 = 60%, P 95 = 32.57%; heterozygosity H = 0.12; the observed allele number n a = 1.6; the effective allele number n e = 1.18; the within-population differentiation ϑs = 0.388; and Shannon index I = 0.19. The degree of genetic isolation of individual local populations was greatly variable. The genetic subdivision index G st varied from 0.162 to 0.770 at the gene flow of Nm = 2.58−0.149, while the among-population distances D N varied from 0.026 to 0.178. The largest part of the genetic diversity was found among the populations (H T = 0.125), while the within-population diversity was twice lower (H S = 0.06). The samples examined were well discriminated relative to the sets of RAPD markers. The character distribution pattern provided conditional subdivision of the mice into the “western” and the “eastern” groups with the putative boarder along the Baikal Lake. The first group was characterized by the prevalence of the markers typical of M. m. musculus and M. m. domesticus. The second group was characterized by the prevalence of the markers typical of M. m. musculus, M. m. gansuensis, M. m. castaneus, M. m. domesticus, and M. m. wagneri. The genotype of the nominative subspecies M. m. musculus was background for all populations. In the populations examined some of earlier described subspecies-specific molecular markers were found at different frequencies, pointing to the involvement of several subspecies of M. musculus in the process of hybridization.

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Authors and Affiliations

  1. Institute of Biology and Soil Science, Russian Academy of Sciences, Vladivostok, 690022, Russia

    L. N. Spiridonova & K. V. Korobitsyna

  2. Vladivostok State University of Economics and Service, Vladivostok, 690990, Russia

    L. V. Yakimenko

  3. Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, 119334, Russia

    A. S. Bogdanov

Authors
  1. L. N. Spiridonova
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  2. K. V. Korobitsyna
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  3. L. V. Yakimenko
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  4. A. S. Bogdanov
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Correspondence to L. N. Spiridonova.

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Original Russian Text © L.N. Spiridonova, K.V. Korobitsyna, L.V. Yakimenko, A.S. Bogdanov, 2008, published in Genetika, 2008, Vol. 44, No. 5, pp. 674–685.

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Spiridonova, L.N., Korobitsyna, K.V., Yakimenko, L.V. et al. Genetic diversity of the house mouse Mus musculus and geographic distribution of its subspecies-specific RAPD markers on the territory of Russia. Russ J Genet 44, 584–594 (2008). https://doi.org/10.1134/S1022795408050116

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