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Hyperthermia of male Drosophila melanogaster meiocytes induces abnormalities in both paternal and maternal sex chromosome sets of the offspring

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Abstract

Nondisjunction and loss of sex chromosomes caused by exposure of male Drosophila melanogaster to heat shock (HS) (37°C for 1 h) has been studied to determine the role of mutation l(1)ts403 (sbr 10) in the control of chromosome segregation during cell division. Hyperthermia of males at the pupal stage has been demonstrated to increase the number of offspring with abnormalities of not only paternal, but also maternal sex chromosome sets. According to the criterion used, there is a temperature-sensitive period of spermatogenesis, which presumably coincides with meiosis. Phenotypes of some individuals correspond to the presence of two sex chromosomes of obtained from the same parent. The frequency of abnormal chromosome sets in the off-spring of male carriers of the sbr 10 mutation is about two times higher than in the offspring of males without this mutation.

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  1. Department of Genetics and Breeding, St. Petersburg State University, St. Petersburg, 199034, Russia

    A. V. K’ergaard & L. A. Mamon

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  1. A. V. K’ergaard
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  2. L. A. Mamon
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Correspondence to L. A. Mamon.

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Original Russian Text © A.V. K’ergaard, L.A. Mamon, 2007, published in Genetika, 2007, Vol. 43, No. 10, pp. 1379–1387.

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K’ergaard, A.V., Mamon, L.A. Hyperthermia of male Drosophila melanogaster meiocytes induces abnormalities in both paternal and maternal sex chromosome sets of the offspring. Russ J Genet 43, 1153–1160 (2007). https://doi.org/10.1134/S1022795407100092

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