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Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system

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Abstract

Humanine is a human neuroprotective peptide with a wide action spectrum. To analyze molecular mechanisms of humanin functioning, a search for proteins interacting with this peptide was conducted using yeast two-hybrid system. Screening of human fetal brain cDNA library identified seven proteins with different functions that specifically interacted with humanin.

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Authors and Affiliations

  1. Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia

    V. V. Maximov, I. P. Arman & V. Z. Tarantul

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  1. V. V. Maximov
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  2. I. P. Arman
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  3. V. Z. Tarantul
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Additional information

Original Russian Text © V.V. Maximov, I.P. Arman, V.Z. Tarantul, 2006, published in Genetika, 2006, Vol. 42, No. 2, pp. 274–277.

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Maximov, V.V., Arman, I.P. & Tarantul, V.Z. Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system. Russ J Genet 42, 208–211 (2006). https://doi.org/10.1134/S1022795406020141

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  • DOI: https://doi.org/10.1134/S1022795406020141

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