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Physicochemical, Sorption, and Morphological Characteristics of Bombyx Mori Silkworm Cocoon Fibroin and a Multifunctional Hemosorbent Obtained on Its Basis

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Abstract

Using fibroin derived from Bombyx mori silkworm cocoons multifunctional hemosorbents for the detoxification of blood and blood serum are obtained. Their physicochemical and morphological properties and sorption behavior are studied. It is shown that the resulting hemosorbents exhibit a high sorption activity. In terms of sorption activity, the hemosorbent based on fibroin treated by ultrasound and microwave irradiation ranks above the commercial hemosorbent VNIITU-1 in the Gemos®-KS hemosorption column (NPP Biotech-М).

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Funding

This work was supported by the scientific research program of the Institute of Polymer Chemistry and Physics, Academy of Sciences of the Republic of Uzbekistan for 2020–2024 “Fundamental Aspects of Creating Nanostructured Polymer Forms of Drugs and Medical Devices—the Future of Nanoparticles in the Body.”

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Authors and Affiliations

  1. Institute of Polymer Chemistry and Physics, Academy of Sciences of the Republic of, 100128, Tashkent, Uzbekistan

    A. A. Sarymsakov, S. S. Yarmatov & Kh. E. Yunusov

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  1. A. A. Sarymsakov
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  2. S. S. Yarmatov
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  3. Kh. E. Yunusov
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Correspondence to Kh. E. Yunusov.

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The authors declare that they have no conflicts of interest.

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Translated by T. Soboleva

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Sarymsakov, A.A., Yarmatov, S.S. & Yunusov, K.E. Physicochemical, Sorption, and Morphological Characteristics of Bombyx Mori Silkworm Cocoon Fibroin and a Multifunctional Hemosorbent Obtained on Its Basis. Polym. Sci. Ser. A 65, 256–263 (2023). https://doi.org/10.1134/S0965545X23700906

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  • DOI: https://doi.org/10.1134/S0965545X23700906

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