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The Concept of Allostasis and Autonomic Regulation in Space Flight

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Abstract

The review presents literature sources confirming the key aspects of the theory of allostasis and its relationship with the theory of homeostasis, as well as some neurophysiological aspects of allostatic systems, which include autonomic regulation, which determine the relationship between the brain and the cardiovascular system. One of the aspects of allostatic regulation is heart rate variability, which reflects the state of the body’s plastic constants and their changes under space flight conditions.

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Notes

  1. We assign this role to the cardiovascular system in view of the fact that it is a determining link in a number of so-called integrative functions of the body: physical performance, orthostatic and vestibulo-vegetative stability, thermoregulation, etc.

  2. In cybernetics and management theory, setting (set point) is the target value for the essential system variable. The deviation of such a variable from the set value is the basis for error control regulation using a negative feedback.

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The review was prepared within Russian Academy of Sciences topics 64.1 and 65.3 for 2013–2023.

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    V. B. Rusanov, I. M. Larina & A. M. Nosovsky

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  1. V. B. Rusanov
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Rusanov, V.B., Larina, I.M. & Nosovsky, A.M. The Concept of Allostasis and Autonomic Regulation in Space Flight. Hum Physiol 49, 699–708 (2023). https://doi.org/10.1134/S0362119723700470

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