Abstract
This review contains the results of the studies of the hemostasis system in airline passengers and crew members, as well as ground-based model experiments simulating the effect of specific flight factors. According to most researchers, flight factors shift the coagulation balance towards increasing the procoagulant potential. However, the occurrence of thrombotic conditions in passengers is associated with the individual presence of certain endogenous risk factors, such as age, constitution, diseases of the cardiovascular system and hereditary pathology of the hemostasis system, and some types of hormone therapy. Aircraft pilots whose flight time significantly exceeds that of passengers have described cases of thrombosis. No mention of cases of hemorrhagic conditions in civil aviation flight personnel has been found in the available literature.
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Kuzichkin, D.S., Betts, K.V. The Hemostasis System in Airline Passengers and Pilots. Hum Physiol 49, 573–578 (2023). https://doi.org/10.1134/S0362119723600133
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DOI: https://doi.org/10.1134/S0362119723600133