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Kérdö Autonomic Index: Role of Initial Parameters, Areas, and Limitations of the Use

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Abstract

The Kérdö Autonomic Index (KAI) was developed by the Hungarian physician I. Kérdö and was used by Russian physiologists to assess the balance of tone between the sympathetic and parasympathetic nervous systems. KAI gives an indirect characteristic of the vagosympathetic balance in the body without revealing the mechanisms of this balance. It was found that in athletes and patients with hypertension, the correlation between KAI and heart rate (HR) is positive, and between KAI and diastolic blood pressure (BPd) negative, which confirms the ideas of I. Kérdö. A theoretical graphical analysis of the dependence of KAI on its constituent parameters showed that KAI has a decreasing rectilinear dependence on BPd and increasing inverted hyperbolic dependence on HR. KAI reflects vagosympathetic balance in the body to a greater extent in terms of HR and to a lesser extent in terms of BPd. KAI correctly characterizes the vagosympathetic balance in the body of athletes before and after physical activity. The use of KAI to assess vagosympathetic balance in patients with hypertension is not recommended. With high blood pressure in hypertensive patients, KAI values can lead to an erroneous conclusion about the vagosympathetic balance in the body.

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REFERENCES

  1. Kérdö, I., Ein aus Daten der Blutzirkulation kalkulierter Index zur Beurteilung der Autonomicn Tonuslage, Acta Neuroveg., 1966, vol. 29, no. 2, p. 250.

    Article  Google Scholar 

  2. Vegetativnye rasstroistva: klinika, lechenie i diagnostika (Autonomic Disorders: Clinics, Therapy, and Diagnostics), Vein, A.M., Ed., Moscow: Med. Inf. Agentstvo, 2000.

    Google Scholar 

  3. Vein, A.M., Solov’eva, A.D., and Kolosova, O.A., Vegetososudistaya distoniya (Vegetovascular Dystonia), Moscow: Meditsina, 1981.

  4. Krivolapchuk, I.A., Factor structure of the functional state of five- and six-year-old children, Hum. Physiol., 2014, vol. 40, no. 5, p. 513.

    Article  Google Scholar 

  5. Krivolapchuk, I.A. and Chernova, M.B., The factor structure of the functional state of boys aged 13–14 years, Hum. Physiol., 2017, vol. 43, no. 2, p. 157.

    Article  Google Scholar 

  6. Ilyukhina, V.A., Krivoshchapova, M.N., and Manzhosova, G.V., Characteristics of the cerebral mechanisms controlling the level of wakefulness, the maturity of cognitive functions, and adaptive responses in children with attention deficit hyperactivity disorder and healthy children of the same age, Hum. Physiol., 2011, vol. 37, no. 2, p. 148.

    Article  Google Scholar 

  7. Buduk-ool, L.K., Aizman, R.I., and Krasilnikova, V.A., The time required for adapting to academic load for students living in a climatically uncomfortable geographic region, Hum. Physiol., 2009, vol. 35, no. 4, p. 484.

    Article  Google Scholar 

  8. Poborsky, A.N., Yurina, M.A., Lopatskaya, Zh.N., and Deryagina, E.Yu., The level of anxiety and state of autonomic regulation depending on the predicted examination grades in students living under unfavorable environmental conditions, Hum. Physiol., 2009, vol. 35, no. 4, p. 416.

    Article  Google Scholar 

  9. Solonin, Yu.G., Markov, A.L., Boyko, E.R., et al., Functional indices in participants of the satellite study on the Mars-500 project in the Russian north during different seasons, Hum. Physiol., 2014, vol. 40, no. 6, p. 634.

    Article  CAS  Google Scholar 

  10. Solonin, Yu.G., Markov, A.L., Boyko, E.R., et al., Comparison of the results of satellite studies of the Mars-500 experiment in Syktyvkar and Almaty, Hum. Physiol., 2015, vol. 41, no. 3, p. 311.

    Article  Google Scholar 

  11. Avilov, O.V. and Sudakov, K.V., Effects of olfactory stimuli on students with different tones of the autonomic nervous system, Hum. Physiol., 2008, vol. 34, no. 6, p. 709.

    Article  Google Scholar 

  12. Graevskaya, N.D. and Dolmatova, T.I., Sportivnaya meditsina: kurs lektsii i prakticheskikh zanyatii (Sports Medicine: Lectures and Practice), Moscow: Sovetskii Sport, 2004.

  13. Fudin, N.A., Klassina, S.Ya., and Vaguine, Yu.E., Rhythmic thermal impacts as a means of restoring persons engaged in physical training and sport after intensive physical activity, Vestn. Nov. Med. Tekhnol., 2013, vol. 20, no. 4, p. 74.

    Google Scholar 

  14. Fudin, N.A., Klassina, S.Ya., Vaguine, Yu.E., and Pigareva, S.N., Physiology of the impact of hypoventilation breathing on the cardiorespiratory and muscular human system during physical work until failure, Sport. Med.: Nauka Prakt., 2016, vol. 6, no. 3, p. 22.

    Article  Google Scholar 

  15. Fudin, N.A. and Klassina, S.Ya., Influence of hypoventilation breathing on cardiorespiratory indices of the persons with different initially dominant Autonomic tone during physical work until failure, Vestn. Nov. Med. Tekhnol., 2017, vol. 24, no. 3, p. 128.

    Google Scholar 

  16. Sudakov, K.V., Andrianov, V.V., Vaguine, Yu.E., et al., Normal’naya fiziologiya: uchebnik (Normal Physiology: A Manual), Moscow: GEOTAR-Media, 2012.

  17. Andrianov, V.V., Badikov, V.I., Bunina, T.P., et al., Normal’naya fiziologiya: praktikum (Normal Physiology: Practical Manual), Moscow: Med. Inf. Agentstvo, 2016.

  18. Sudakov, K.V., Andrianov, V.V., Vaguine, Yu.E., and Kiselev, I.I., Fiziologiya cheloveka: atlas dinamicheskikh sistem (Human Physiology: Atlas of Dynamic Systems), Moscow: GEOTAR-Media, 2018.

  19. Zaitsev, D.N. and Govorin, A.V., The markers of endothelial dysfunction in patients with chronic prostatitis, Arterial’naya Gipertenziya, 2015, vol. 21, no. 4, p. 436.

    Article  Google Scholar 

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Authors and Affiliations

  1. Sechenov First Moscow State Medical University (Sechenov University), 119146, Moscow, Russia

    Yu. E. Vaguine, S. M. Deunezhewa & A. A. Khlytina

  2. Anokhin Research Institute of Normal Physiology, Russian Academy of Sciences, 125315, Moscow, Russia

    Yu. E. Vaguine, S. M. Deunezhewa & A. A. Khlytina

Authors
  1. Yu. E. Vaguine
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  2. S. M. Deunezhewa
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  3. A. A. Khlytina
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Correspondence to Yu. E. Vaguine.

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COMPLIANCE WITH ETHICAL STANDARDS

All procedures performed in studies involving human participants were in accordance with the biomedical ethics principles formulated in the 1964 Helsinki Declaration and its later amendments and approved by the local bioethics commission of the Anokhin Research Institute of Normal Physiology, Russian Academy of Sciences (Moscow, Russia).

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The authors declare that they have no conflict of interest connected with the publication of this article.

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Informed written consent was obtained from all individual participants involved in the study and signed by them after being explained the potential risks and advantages, as well as the essence of the future study.

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Translated by E. Babchenko

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Vaguine, Y.E., Deunezhewa, S.M. & Khlytina, A.A. Kérdö Autonomic Index: Role of Initial Parameters, Areas, and Limitations of the Use. Hum Physiol 47, 23–32 (2021). https://doi.org/10.1134/S0362119720060122

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  • DOI: https://doi.org/10.1134/S0362119720060122

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