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Synchronous Changes in Microcirculation Parameters of the Upper Limbs in Asymmetric Physical Loads

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Abstract

This is the first study on synchronous changes in microcirculation in the symmetrical organs of humans during asymmetric physical loads of the upper limbs. The study was conducted in healthy volunteers by the method of laser Doppler flowmetry (LDF). LDF signal transducers were fixed symmetrically on the lower parts of the right and left shoulders (3 cm above the elbow bend). Physical loads included the left or right arm swings in standing position for 1 min. Measurements were made in three states: (1) initial state, (2) immediately after physical activity, and (3) 5 min after loads. The changes in the mean perfusion value and the components of amplitude-frequency spectrum of blood flow fluctuations (myogenic, neurogenic, respiratory, and cardiac) were evaluated in both sides of the body. We observed the asymmetry of changes in microcirculation parameters after physical loads. It is shown that both left and right swings change the microcirculation parameters of both the left and right sides, and the changes on the left are more pronounced than on the right. A nonlinear relationship was observed between the changes in microcirculation parameters of symmetrical areas of paired organs and heart rate. Our data illustrate the specific regulation patterns of microcirculation blood flow in paired organs, which is associated with functional asymmetry. The physiological mechanisms of this asymmetry require further experimental and clinical research.

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REFERENCES

  1. Chernukh, A.M., Aleksandrov, P.N., and Alekseev, O.V., Mikrotsirkulyatsiya (Microcirculation), Moscow: Meditsina, 1984.

    Google Scholar 

  2. Krupatkin, A.I., Oscillatory processes in the diagnosis of the state of microvascular-tissue systems, Hum. Phys., 2018, vol. 44, no. 5, p. 581.

    Article  Google Scholar 

  3. Shchurov, V.A., Dynamics of the speed of blood flow in the arteries of the bone regenerate of the limbs and in the brain arteries during functional tests and changes in the treatment mode, Reg. Krovoobrashch. Mikrotsirkulyatsiya, 2018, vol. 17, no. 4, p. 51.

    Google Scholar 

  4. Goltsov, A., Anisimova, A., Zakharkina, A., et al., Bifurcation in blood oscillatory rhythms for patients with ischemic stroke: a small scale clinical trial using laser Doppler flowmetry and computational modeling of vasomotion, Front. Physiol., 2017, vol. 8, p. 160.

    Article  Google Scholar 

  5. Kozlov, V.I. and Tupitsin, I.O., Mikrotsirkulyatsiya pri myshechnoi deyatel’nosti (Microcirculation during Muscular Activity), Moscow: Fizkul’tura i Sport, 1982.

  6. Mikhailichenko, L.A. and Reutov, M.I., Asymmetry during regeneration of microvessels in rabbit ear, Bull. Exp. Biol. Med., 1997, vol. 123, no. 3, p. 298.

    Article  Google Scholar 

  7. Mikhailichenko, L.A. and Aleksandrov, P.N., Analysis of skin microcirculation in rats near inflammation spot based on laser Doppler flowmetry, Reg. Krovoobrashch. Mikrotsirkulyatsiya, 2005, vol. 4, no. 4 (18), p. 79.

  8. Mikhailichenko, L.A., Microcirculation indicators of paired organs and tissues of experimental healthy animals, Reg. Krovoobrashch. Mikrotsirkulyatsiya, 2007, vol. 6, no. 1 (21), p. 164.

  9. Benedicic, M., Dolenc, V.V., Stefanovska, A., and Bosnjak, R., Left-right asymmetry of the facial microvascular control, Clin. Auton. Res., 2006, vol. 16, no. 1, p. 58.

    Article  Google Scholar 

  10. Mezentseva, L.V. and Pertsov, S.S., Correlation-and-spectral analysis of time series for microcirculatory parameters in vessels of symmetrical organs, Bull. Exp. B-iol. Med., 2019, vol. 166, no. 3, p. 301.

    Article  CAS  Google Scholar 

  11. Krupatkin, A.I., Sidorov, V.V., and Kutepov, I.A., The analysis of information processes in microvascular networks using wavelet analysis of the oscillatory structures of blood flow, Reg. Krovoobrashch. Mikrotsirkulyatsiya, 2009, vol. 8, no. 3 (31), p. 21.

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Funding

The work was supported by resources of the Federal budget of the Russian Federation in accordance with the State Order for the Anokhin Research Institute of Normal Physiology (Moscow).

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Authors and Affiliations

  1. Anokhin Research Institute of Normal Physiology, Moscow, Russia

    L. V. Mezentseva & S. S. Pertsov

  2. Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia

    S. S. Pertsov

Authors
  1. L. V. Mezentseva
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  2. S. S. Pertsov
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Correspondence to L. V. Mezentseva.

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Conflict of interests. The authors declare that they have no conflict of interest.

Statement of compliance with standards of research involving humans as subjects. All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants involved in the study.

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Translated by E.V. Makeeva

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Mezentseva, L.V., Pertsov, S.S. Synchronous Changes in Microcirculation Parameters of the Upper Limbs in Asymmetric Physical Loads. Hum Physiol 46, 671–676 (2020). https://doi.org/10.1134/S036211972004009X

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  • DOI: https://doi.org/10.1134/S036211972004009X

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