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Parameters of Psychoverbal Development and Sleep Structure in Preschool Children with Obstructive Sleep Apnea

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A complex examination revealed the features of the development of higher cortical functions and sleep clinical features in preschool children with obstructive sleep apnea. Typical features were identified in the macrostructure of sleep and its cyclic organization in the children. Connective tissue dysplasia proved to act as a significant etiological factor in the pathogenesis of obstructive sleep apnea–hypopnea syndrome (OSAHS) in children. The effect of OSAHS on the cognitive development of children was investigated. Ontogenetic features were identified in the formation of OSAHS in preschool children. Signs of multicomponent and multilevel dysontogenetic syndrome were observed, including distorted maturation of basic higher cortical functions and alterations of the macrostructure and cyclic organization of sleep.

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Correspondence to T. P. Kalashnikova.

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Statement of compliance with standards of research involving humans as subjects. All procedures were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments and were approved by the local Ethics Committee at the Academician Wagner Perm State Medical University (Ministry of Health of the Russian Federation, Perm). All individual participants involved in the study voluntarily gave their written informed consent for participation after being informed about potential risk and benefits and the nature of the study.

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Translated by T. Tkacheva

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Kalashnikova, T.P., Anisimov, G.V. & Yastrebova, A.V. Parameters of Psychoverbal Development and Sleep Structure in Preschool Children with Obstructive Sleep Apnea. Hum Physiol 46, 295–299 (2020). https://doi.org/10.1134/S0362119720030056

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  • DOI: https://doi.org/10.1134/S0362119720030056

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