A complex examination revealed the features of the development of higher cortical functions and sleep clinical features in preschool children with obstructive sleep apnea. Typical features were identified in the macrostructure of sleep and its cyclic organization in the children. Connective tissue dysplasia proved to act as a significant etiological factor in the pathogenesis of obstructive sleep apnea–hypopnea syndrome (OSAHS) in children. The effect of OSAHS on the cognitive development of children was investigated. Ontogenetic features were identified in the formation of OSAHS in preschool children. Signs of multicomponent and multilevel dysontogenetic syndrome were observed, including distorted maturation of basic higher cortical functions and alterations of the macrostructure and cyclic organization of sleep.
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REFERENCES
Guilleminault, C., Connolly, S.J., and Winkle, R.A., Cardiac arrhythmia and conduction disturbances during sleep in 400 patients with sleep apnea syndrome, Am. J. Cardiol., 1983, vol. 52, no. 5, p. 490.
Prokhorova, A.D., Blokhin, D.B., Poluektov, M.G., and Delyagin, V.M., Obstructive sleep apnea syndrome and obesity in children: common ground, Prakt. Pediatra, 2017, no. 4, p. 7.
Strueva, N.V., Savel’eva, L.V., Mel’nichenko, G.A., et al., Personalized treatment of obesity complicated by obstructive sleep apnea, Ozhirenie Metab., 2014, vol. 1, p. 48.
Bhattacharjee, R., Kim, J., Alotaibi, W.H., et al., Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea, Chest, 2012, vol. 141, no. 3, p. 682.
Kel’manson, I.A., Intellectual disorders and sleep disorders in children, Vrach, 2015, no. 1, p. 2.
Kel’manson, I.A., Sleep disorders in children with mental retardation, Vopr. Sovrem. Pediatr., 2014, vol. 13, no. 6, p. 15.
Lisovskaya, N.A., Korostovtseva, L.S., Dubinina, E.A., et al., The relationship of obstructive sleep apnea during sleep with cognitive impairment in children, Arterial’naya Gipertenziya, 2015, vol. 21, no. 1, p. 101.
Nemkova, S.A., Maslova, O.I., Zavadenko, N.N., et al., Complex diagnosis and correction of sleep disorders in children, Pediatr. Farmakol., 2015, vol. 12, no. 2, p. 180.
Kalashnikova, T.P., Anisimov, G.V., and Kon’shina, N.V., Characterization of sleep in children with attention deficit hyperactivity disorder, Spets. Obraz., 2013, no. 3, p. 72.
Huang, J., Marcus, C.L., Davenport, P.W., et al., Respiratory and auditory cortical processing in children with obstructive sleep apnea syndrome, Am. J. Respir. Crit. Care Med., 2013, vol. 188, no. 7, p. 852.
Schwengel, D.A., Dalesio, N.M., and Stierer, T.L., Pediatric obstructive sleep apnea, Anesthesiol. Clin., 2014, vol. 32, no. 1, p. 237.
Spork, P., Das Schlafbuch: Warum wir Schlafen und Wie es Uns am Besten Gelingt, Reinbek: Rowohlt, 2007.
Pal’chik, A.B., Lektsii po nevrologii razvitiya (Lectures on Developmental Neurology), Moscow: MEDpress-Inform, 2017, 3rd ed.
Pal’chik, A.B., Evoulyutsionnaya nevrologiya (Evolutionary Neurology), St. Petersburg: Piter, 2002.
Beighton, P., De Paepe, A., Steinmann, B., et al., Ehlers-Danlos syndromes: revised nosology, Villefranche, Am. J. Med. Genet., 1998, vol. 77, no. 1, p. 31.
Golovei, L.A. and Rybalko, E.F., Praktikum po vozrastnoi psikhikhologii (Practical Manual on Developmental Psychology), St. Petersburg: Rech’, 2002, p. 271.
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Statement of compliance with standards of research involving humans as subjects. All procedures were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments and were approved by the local Ethics Committee at the Academician Wagner Perm State Medical University (Ministry of Health of the Russian Federation, Perm). All individual participants involved in the study voluntarily gave their written informed consent for participation after being informed about potential risk and benefits and the nature of the study.
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Kalashnikova, T.P., Anisimov, G.V. & Yastrebova, A.V. Parameters of Psychoverbal Development and Sleep Structure in Preschool Children with Obstructive Sleep Apnea. Hum Physiol 46, 295–299 (2020). https://doi.org/10.1134/S0362119720030056
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DOI: https://doi.org/10.1134/S0362119720030056