Abstract
Transcranial magnetic stimulation (TMS) is a new technique that results in neuron excitation using alternating magnetic fields. According to recent reports, high-frequency TMS could be an effective treatment for drug-resistant central post-stroke pain (CPSP). The present case report describes the clinical observation of two patients with CPSP with different lesion localisations and volumes. High frequency (10 Hz) TMS of the primary motor cortex of the affected hemisphere was used in each patient. After stimulation, we recorded a significant reduction in pain on a visual analogue scale (VAS). However, after the end of treatment with TMS, pain gradually returned to previous levels after 3–4 months.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Nikitin, S.S. and Kurenkov, A.L., Magnitnaya stimulyatsiya v diagnostike i lechenii boleznei nervnoi sistemy. Rukovodstvo dlya vrachei (Magnetic stimulation in the diagnosis and treatment of nervous system diseases: Handbook for doctors), Moscow: SAShKO, 2003.
Sashina, M.V., Rehabilitation of patients with central post-stroke pain syndrome, Cand. Sci. (Med.) Dissertation, 2005.
André-Obadia, N., Peyron, R., Mertens, P., et al., Transcranial magnetic stimulation for pain control. Double-blind study of different frequencies against placebo, and correlation with motor cortex stimulation efficacy, Clin. Neurophysiol., 2006, vol. 117, no. 7, p. 1536.
Canavero, S. and Bonicalzi, V., The neurochemistry of central pain: Evidence from clinical studies, hypothesis and therapeutic implications, Pain, 1998, vol. 74, nos. 2–3, p. 109.
Cruccu, G., Aziz, T.Z., Garcia-Larrea, L., et al., EFNS guidelines on neurostimulation therapy for neuropathic pain, Eur. J. Neurol., 2007, vol. 14, no. 9, p. 952.
Khedr, E.M., Kotb, H., Kamel, N.F., et al., Long-lasting antalgic effects of daily sessions of repetitive transcranial magnetic stimulation in central and peripheral neuropathic pain, J. Neurol., Neurosurg. Psychiatry, 2005, vol. 76, no. 6, p. 833.
Klit, H., Finnerup, N.B., and Jensen, T.S., Central poststroke pain: Clinical characteristics, pathophysiology, and management, Lancet Neurol., 2009, vol. 8, no. 9, p. 857. doi 10.1016/S1474-4422(09)70176-0
Kumar, B., Kalita, J., Kumar, G., and Misra, U.K., Central poststroke pain: a review of pathophysiology and treatment, Anesth. Analg., 2009, vol. 108, no. 5, p. 1645. doi 10.1213/ane.0b013e31819d644c
Laterre, E.C., De Volder, A.G., and Goffinet, A.M., Brain glucose metabolism in thalamic syndrome, J. Neurol., Neurosurg. Psychiatry, 1988, vol. 51, no. 3, p. 427.
Lefaucheur, J.P., Drouot, X., Ménard-Lefaucheur, I., and Nguyen, J.P., Neuropathic pain controlled for more than a year by monthly sessions of repetitive transcranial magnetic stimulation of the motor cortex, Neurophysiol. Clin., 2004, vol. 34, no. 2, p. 91.
Nasreddine, Z.S. and Saver, J.L., Pain after thalamic stroke: Right diencephalic predominance and clinical features in 180 patients, Neurology, 1997, vol. 48, no. 5, p. 1196.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © A.V. Cherviakov, A.V. Belopasova, A.G. Poydasheva, L.A. Chernikova, A.S. Kadykov, N.A. Suponeva, M.A. Piradov, 2013, published in Annaly Klinicheskoi i Eksperimental’noi Nevrologii, 2013, Vol. 7, No. 4, pp. 45–50.
Rights and permissions
About this article
Cite this article
Cherviakov, A.V., Belopasova, A.V., Poydasheva, A.G. et al. Transcranial magnetic stimulation for the treatment of central post-stroke pain. Hum Physiol 42, 844–849 (2016). https://doi.org/10.1134/S036211971608003X
Published:
Issue Date:
DOI: https://doi.org/10.1134/S036211971608003X