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Status of the hemostasis system in hypoxic nitrogen-oxygen and argon-oxygen diving gases

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Abstract

The effect of factors of a hermetic chamber with a modified atmosphere on the hemostasis system was studied in order to evaluate and to compare different diving breathing gases. The parameters characterizing procoagulant, anticoagulant, and fibrinolytic components of hemostasis were determined by clotting, chromogenic, and immunological methods. The test exposure did not significantly affect activity and the regulatory potential of hemostasis. However, nitrogen-oxygen and argon-oxygen hypoxic diving gases exerted different effects on hemostasis, which were especially distinct in the recovery period.

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References

  1. Pak, G.D., Sverchkova, V.S., and Danilevskaya, T.N., Hemostasis system in hypoxic hypoxia varying in extent, Aviakosmich. Med., 1990, vol. 24, no. 2 p. 4.

    CAS  Google Scholar 

  2. Torgovicky, R., Azaria, B., Grossman, A., et al., Sinus vein thrombosis following exposure to simulated high altitude, Aviat. Space Environ. Med., 2005, vol. 76, no. 2 p. 144.

    PubMed  Google Scholar 

  3. Schreijer, A.J.M., Hoylaerts, M.F., Meijers, J.C.M., et al., Explanations for coagulation activation after air travel, J. Thrombosis Haemostasis, 2010, vol. 8, no. 5 p. 971.

    CAS  Google Scholar 

  4. Ozsoylu, S. and Dimersoy, F., Oxygen concentration and factor-VIII procoagulant activity, Acta Haematol., 1982, vol. 68, no. 4 p. 333.

    Article  CAS  PubMed  Google Scholar 

  5. Pak, G.D., Sverchkova, V.S., and Trandafilova, T.P., Changes in blood clotting activity in acute hypoxic hypoxia, Fiziol. Zh. SSSR im. I.M. Sechenova, 1987, vol. 53, no. 1 p. 130.

    Google Scholar 

  6. Hodkinson, P.D., Hunt, B.J., Parmar, K., et al., Is mild normobaric hypoxia a risk factor for venous thromboembolism?, J. Thrombosis Haemostasis, 2003, vol. 1, no. 10 p. 2131.

    Article  CAS  Google Scholar 

  7. Mantysaari, M., Joutsi-Korhonen, L., Siimes, M.A., et al., Unaltered blood coagulation and platelet function in healthy subjects exposed to acute hypoxia, Aviation, Space, Environ. Med., 2011, vol. 82, no. 7 p. 699.

    Google Scholar 

  8. N’yuskholm, E. and Start, K., Regulyatsiya metabolizma (Metabolic Regulation), Moscow, 1977.

    Google Scholar 

  9. Rebrova, R.Yu., Statisticheskii analiz meditsinskikh dannykh (Statistical Analysis of Medical Data), Moscow, 2006.

    Google Scholar 

  10. De Loughery, T.G., Robertson, D.G., Smith, C.A., et al., Moderate hypoxia suppresses exercise-induced procoagulant changes, Brit. J. Haematol., 2004, vol. 125, no. 3 p. 369.

    Article  Google Scholar 

  11. Vij, A., Effect of prolonged stay at high altitude on platelet aggregation and fibrinogen levels, Platelets, 2009, vol. 20, no. 6 p. 421.

    Article  CAS  PubMed  Google Scholar 

  12. Dorokhova, E.I., Blood coagulation in prolonged hypodynamia as revealed by thromboelastography, in Problemy kosmicheskoi biologii (Problems of Space Biology), Moscow, 1969, vol. 13, p. 109.

    Google Scholar 

  13. Byshevskii, A.Sh. and Kozhevnikov, V.N., Svertyvaemost’ krovi pri reaktsiyakh napryazheniya (Blood Coagulation in Stress Responses), Sverdlovsk, 1986.

    Google Scholar 

  14. Zubairov, D.M., Molekulyarnye osnovy svertyvaniya krovi i tromboobrazovaniya (Molecular Basis of Blood Clotting and Thrombosis), Kazan, 2000.

    Google Scholar 

  15. Pinsky, D.J., Yan, S.F., Lawson, C., et al., Hypoxia and modification of the endothelium: Implications for regulation of vascular homeostatic properties, Seminars Cell Biol., 1995, vol. 6, no. 5 p. 283.

    Article  CAS  Google Scholar 

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Correspondence to A. A. Markin.

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Original Russian Text © D.S. Kuzichkin, A.A. Markin, O.A. Juravlyova, B.V. Morukov, I.V. Zabolotskaya, L.V. Vostrikova, 2015, published in Fiziologiya Cheloveka, 2015, Vol. 41, No. 4, pp. 132–136.

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Kuzichkin, D.S., Markin, A.A., Juravlyova, O.A. et al. Status of the hemostasis system in hypoxic nitrogen-oxygen and argon-oxygen diving gases. Hum Physiol 41, 455–458 (2015). https://doi.org/10.1134/S036211971503010X

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  • DOI: https://doi.org/10.1134/S036211971503010X

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