Abstract
Six male volunteers (25 to 40 years old) were subjects in integrated psychophysiological, hormonal, and immunological studies before, during, and after 105-day isolation and confinement. Blood was taken and the Cattell’s 16 personality factor questionnaire was filled out every 30 days. Concentrations of blood hormones, neurospecific proteins, and cytokines point out to a close interrelation between the titers of antibodies to the myelin-associated glycoprotein and changes in psychophysiological, immunological, and hormonal parameters characterizing the metabolism rate and reproductive function, blood concentrations of cytokines, and individual psychophysiological characteristics (extra-introversion, dominance, intropunitiveness, social contact selectivity, etc.) and suggest a minimum risk of development of autoimmune demyelinizing neuropathies during in isolation and confinement with an altered environment.
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Original Russian Text © I.A. Nichiporuk, G.Yu. Vasilieva, M.P. Rykova, B.V. Morukov, 2011, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2011, Vol. 45, No. 3, pp. 24–29.
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Nichiporuk, I.A., Vasilieva, G.Y., Rykova, M.P. et al. Dynamics of blood concentration of neurospecific proteins and risk of neuropathy development in the conditions of 105-day isolation and confinement. Hum Physiol 40, 790–796 (2014). https://doi.org/10.1134/S0362119714070159
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DOI: https://doi.org/10.1134/S0362119714070159