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Functional load tests in the assessment of the state of the kidneys and water-electrolyte metabolism

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The Editorial Board and editors of “Fiziologiya Cheloveka” (Human Physiology) congratulate Anatolii Ivanovich Grigoriev on his jubilee and wish him good health, happiness, much creative success, and new scientific achievements.

Abstract

The use of functional load tests to assess the specific features of water-electrolyte metabolism under extreme conditions is considered, with special emphasis on their implications for space physiology and medicine. Water and mineral metabolism, the kidney function, and their hormonal regulation during simulation experiments, as well as in spaceflights and in the readaptation period, play an important role in human adaptation to new conditions of vital activity. In order to assess the state of the kidneys and water-electrolyte metabolism in cosmonauts and investigators, functional load tests were developed. They enabled us not only to gain insight into the mechanisms of osmotic and volumetric regulation but also to develop countermeasures to correct unfavorable shifts in water-salt homeostasis.

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Authors and Affiliations

  1. Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia

    A. I. Grigoriev & V. B. Noskov

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  1. A. I. Grigoriev
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  2. V. B. Noskov
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Original Russian Text © A.I. Grigoriev, V.B. Noskov, 2013, published in Fiziologiya Cheloveka, 2013, Vol. 39, No. 2, pp. 10–18.

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Grigoriev, A.I., Noskov, V.B. Functional load tests in the assessment of the state of the kidneys and water-electrolyte metabolism. Hum Physiol 39, 119–125 (2013). https://doi.org/10.1134/S0362119713020060

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