Abstract
We studied the effect of a 105-day experiment in an isolated environment on the functional state of the cardiovascular system of six male participants aged 25 to 40 years; as well as the diagnostic significance of novel research methods, in particular, the ECG variance mapping and the assessment of endotheliumdependent flow mediated dilation in the right brachial artery. Our results indicate that the conditions of isolation resulted in changes in the internal cardiac hemodynamics and, consequently, to progressive development of cardiac arrhythmias. This is probably related to the changes in neurohumoral regulation of the heart and disturbance of the sympathetic and parasympathetic innervations. The changes in the vascular wall and vasomotor endothelial function in two subjects suggest endothelial dysfunction and an increased risk of atherosclerosis.
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Original Russian Text © S.P. Builov, Yu.I. Voronkov, M.A. Skedina, G.P. Stepanova, 2010, published in Aviakosmicheskaya i Ekologicheskaya Meditsina, 2010, Vol. 44, No. 4, pp. 27–30.
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Builov, S.P., Voronkov, Y.I., Skedina, M.A. et al. The effect of a 105-day experiment in isolated environment on the functional state of the cardiovascular system of the participants. Hum Physiol 38, 699–702 (2012). https://doi.org/10.1134/S0362119712070079
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DOI: https://doi.org/10.1134/S0362119712070079