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Blood serum concentration of lipids and lipoproteins and body composition

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The goal of this study was to analyze the relationship of the blood serum apolipoprotein E (apoE), total cholesterol (TC), triglycerides (TG), and high- and low-density lipoproteins (HDLP, LDLP) levels with the body mass index (BMI), relative body surface area (RBSA), and the body muscle (BM) and body fat (BF) amounts. The study was carried out in male and female subjects aged 14–16 years (adolescent age group 1: n 1M = 141, n 1F = 151) and 18–25 years (young adult group 2: n 2M = 141, n 2F =46). No significant correlations of serum TG and HDL with the somatometric indices were found. The T-lated with the fat component (r 1 = 0.164; r 2 = 0.418) and negatively, with the muscle component of body composition (r 1 = −0.165; r 2 = −0.352) in female subject samples. Blood serum apoE is significantly correlated with body composition (r 1 = −0.168 for BF; r 1 = 0.266, p < 0.05 for BM) in female adolescent subjects. These correlations are significant (p < 0.06) in male subjects aged 14–16 years. The TC and LDLP contents are negatively correlated with RBSA (r 2 = −0.386 and −0.377, respectively) and positively correlated with BMI (r 2 = 0.413 and 0.415, respectively; p < 0.05) in young adult female subjects. With age, correlations between the fat content and apoE concentration change in female subject samples. The content of apoE decreases with increasing BF in female subjects aged 14–15 years; the correlation disappears in the age interval from 16 to 17 years. An increase in BF is accompanied by an increase in the apoE concentration in female subjects aged 18–19 years and older.

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Authors and Affiliations

  1. Perm State National Pedagogical University, Perm, 614990, Russia

    A. I. Kozlov, G. G. Vershubskaya & Yu. A. Ateeva

  2. Institute of Developmental Physiology, Russian Academy of Education, Moscow, 119121, Russia

    A. I. Kozlov, G. G. Vershubskaya & E. D. Sanina

  3. Vavilov Institute of General Genetics, Russian Academy of Science, Moscow, 119991, Russia

    E. D. Sanina

  4. Institute of Physiology, Ural Branch, Russian Academy of Sciences, Syktyvkar, 167982, Russia

    N. N. Potolitsyna, A. M. Kaneva & E. R. Boiko

  5. Komi State Pedagogical Institute, Syktyvkar, 167982, Russia

    O. V. Rogachevskaya

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  1. A. I. Kozlov
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Original Russian Text © A.I. Kozlov, G.G. Vershubskaya, E.D. Sanina, Yu.A. Ateeva, N.N. Potolitsyna, A.M. Kaneva, O.V. Rogachevskaya, E.R. Boiko, 2012, published in Fiziologiya Cheloveka, 2012, Vol. 38, No. 3, pp. 116–123.

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Kozlov, A.I., Vershubskaya, G.G., Sanina, E.D. et al. Blood serum concentration of lipids and lipoproteins and body composition. Hum Physiol 38, 324–330 (2012). https://doi.org/10.1134/S0362119712020119

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