Abstract
The hypothesis of the exponential dependence of transient processes described by the curve of saturation of arterial blood hemoglobin with oxygen (SaO2) during alternatively breathing a hypoxic mixture (10–13% O2) and room air. A formalized description of the SaO2 curve provides important parameters of the oxygen transportation system and the individual phases of its functioning. The saturation curve characteristic of the transient processes during hypoxic exposure is adequately approximated by the exponential function. The exponential curve parameters are assumed to be useful for estimating the individual hypoxic resistance of the human body.
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References
Read, D.J.C., A Clinical Method for Assessing the Ventilatory Response to Carbon Dioxide, Austral. Ann. Med., 1967, vol. 16, p. 20.
Weil, J.V., Byrne-Quinn, V.E., Sodal, I.E., et al., Hypoxic Ventilatory Response in Man, J. Clin. Invest., 1970, vol. 49, p. 1061.
Vinitskaya, R.S., Tsuzmer, T.S., and Koganova, N.A., The Use of Infrared CO2 Gas Analyzer for the Analysis of Alveolar Air, in Novye pribory gazovogo analiza v sovremennoi meditsine (New Devices for Gas Analysis in Modern Medicine), Kazan: 1967.
Vinitskaya, R.S., Capnography in Diagnosing the Pulmonary Failures, 2002, http://www.medlinks.ru/article.php?sid=5835/
Chizhov, A.Ya., Strelkov, R.B., and Potievskaya, V.I., Normobaricheskaya gipoksiterapiya (metod “Gornyi vozdukh”) (Normobaric Hypoxytherapy: The Mountain Air Method), Agadzhanyan, N.A. Ed., Moscow: RUDN, 1994.
Strelkov, R.B., Normobaricheskaya gipoksiterapiya (Normobaric Hypoxytherapy), Moscow: Minzdrav Rossii, 1994.
Luk’yanova, L.D., Functional and Metabolic Features of Animals with Different Resistance to Hypoxia, in Problemy gipoksii: molekulyarnye, fiziologicheskie i meditsinskie aspekty (The Problems of Hypoxia: Molecular, Physiological, and Medical Aspects), Luk’yanova, L.D. and Ushakov, I.B., Eds, Moscow, 2004, p. 156.
RF Inventor’s Certificate 24098, 2002.
Glazachev, O.S., Orlova, M.A., Babikov, V.I., and Fedyanina, N.G., Individual Approach to System Rehabilitation of Schoolchildren by the Interval Normobaric Hypoxia, Vestn. Novogorodsk. Gos. Univ., 1998, no. 8, p. 23.
Lee, P.I. and Amidon, G.L., Pharmacokinetic Analysis: A Practical Approach, Lancaster: Technomic, 1996.
RF Patent 2 115 366, 1998.
RF Patent 2 150 260, 2000.
Grebenyuk, S.A., Ozarovskii, E.E., Dvornikov, M.V., Stepanov, V.K., and Suponitskii, V.L., Interval Normobaric Hypoxia, Mezhdunar. Akad. problem gipoksii (International Academy on Hypoxia Problems), Moscow: Bumazhnaya Galereya, 2005.
Melnikov, V.N., Metod kolichestvennoi otsenki adaptirovannosti biologicheskikh sistem. Adaptatsiya i adaptogeny (Method of Quantitative Evaluation of Adaptation of Biological Systems), Vladivostok, 1977.
Aleksandrov, O.V., Struchkov, P.V., Vinitskaya, R.S., Tykotskaya, M.A., Polunova, V.M., Shcherbatykh, O.V., Zinova, I.L., Lozhkina, M.A., and Togoev, A.M., Responses of Cardiorespiratory System to Hypoxic Exposure in the Course of Hypoxitherapy in Patients with Chronic Obstructive Pulmonary Disease, Hyp. Med. J., 1997, vol. 5, no. 1, p. 18.
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Original Russian Text © L.T. Kovtun, Yu.A. Tataurov, V.N. Melnikov, S.G. Krivoschekov, 2011, published in Fiziologiya Cheloveka, 2011, Vol. 37, No. 3, pp. 64–69.
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Kovtun, L.T., Tataurov, Y.A., Melnikov, V.N. et al. Saturation of the arterial blood hemoglobin with oxygen (SaO2) in response to breathing a hypoxic mixture. Hum Physiol 37, 324–328 (2011). https://doi.org/10.1134/S0362119711030029
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DOI: https://doi.org/10.1134/S0362119711030029