Abstract
Changes in hemostasis indices in the course of a 105-day hermetic chamber isolation experiment were studied. The following indices were measured: the activated partial thromboplastin time (APTT); the prothrombin time (PT); the prothrombin index (PI); the international normalized ratio (INR); the thrombin time (TT); the concentrations of fibrinogen, soluble fibrin-monomer complexes (SFMC), D-dimer, and plasminogen (PG); and the activities of antithrombin III, protein C, and α2-antiplasmin. Isolation was accompanied by PT prolongation (with PI decreasing and INR increasing) observed until the seventh day of the aftereffect period, as well as a decrease in the PG concentration. The changes are likely to have been related to the specific motor activity mode, the effect of compensatory physical exercise, and changes in the characteristics of protein and lipid metabolisms.
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References
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Original Russian Text © D.S. Kuzichkin, A.A. Markin, B.V. Morukov, 2011, published in Fiziologiya Cheloveka, 2011, Vol. 37, No. 3, pp. 129–131.
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Kuzichkin, D.S., Markin, A.A. & Morukov, B.V. Hemostasis system indices in the course of a 105-day hermetic chamber isolation experiment. Hum Physiol 37, 379–381 (2011). https://doi.org/10.1134/S0362119711020125
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DOI: https://doi.org/10.1134/S0362119711020125