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Energy and fractal characteristics of physiological and pathological tremors of the human hand

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Abstract

Tremors (involuntary shaking) were compared in healthy subjects and patients with the tremulous form of Parkinsonism sustaining isometric effort of the hand. For this purpose, fractal analysis and multilevel wavelet decomposition of tremor were used, and the energy characteristics determined on the basis of the spectral density of the energy of detailed components obtained at different levels of decomposition. The calculated fractal and energy characteristics of the tremor of healthy subjects were significantly lower than those of patients. If the patients took antiparkinsonian drugs at their usual doses, the characteristics shifted towards normal values. The decrease in the fractal dimension indicates an increase in the strength of the correlation in the dynamics of involuntary shaking. Thus, the characteristics studied allow not only physiological and pathological tremors to be discriminated, but also the strategy of selection of optimal drugs for relieving Parkinsonian tremor to be developed.

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Authors and Affiliations

  1. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, 199034, Russia

    O. E. Dick & S. P. Romanov

  2. St. Petersburg State University, St. Petersburg, 199034, Russia

    A. D. Nozdrachev

Authors
  1. O. E. Dick
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  2. S. P. Romanov
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  3. A. D. Nozdrachev
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Original Russian Text © O.E. Dick, S.P. Romanov, A.D. Nozdrachev, 2010, published in Fiziologiya Cheloveka, 2010, Vol. 36, No. 2, pp. 92–100.

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Dick, O.E., Romanov, S.P. & Nozdrachev, A.D. Energy and fractal characteristics of physiological and pathological tremors of the human hand. Hum Physiol 36, 203–210 (2010). https://doi.org/10.1134/S036211971002012X

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  • DOI: https://doi.org/10.1134/S036211971002012X

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