Abstract
Examination of children at the beginning of school education showed that their autonomic regulatory mechanisms were stressed to various degrees, correlated with the rate of energy consumption in cells, which determines their performance and the adaptability to the adverse environment of Western Siberia. Most children displayed initial moderate or high sympathetic hypertonia (35 and 10% of children examined, respectively); in contrast, 26% of first graders were vagotonic. The highly stressed state of the regulatory mechanisms manifested itself as an unfavorable hypersympathicotonic type of autonomic reactivity. This was accompanied by certain cytochemical changes, mainly, a compensatory activation of succinate dehydrogenase, the degree of which depended on the degree of its inhibition. An optimum state of the regulatory mechanisms was found in only 29% of children, and 44% of them displayed a rather stressed state of energy-producing processes, threatening to disturb adaptive processes and the autonomic equilibrium.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adaptatsiya organizma uchashchikhsya k uchebnoi i fizicheskoi nagruzkam (Adaptation of Students to Academic Load and Physical Exercise), Khripkova, A.G. and Antropova, M.V., Eds., Moscow: Pedagogika, 1982.
Fiziologiya razvitiya rebenka. Teoreticheskie i prikladnye aspekty (Physiology of Child Development: Theoretical and Applied Aspects), Bezrukikh, M.M. and Farber, D.A., Eds., Moscow: Obrazovanie, 2000.
Kuchma, V.R., Environmental Problems of Children’s Health Monitoring, Gig. Sanit., 1993, no. 1, p. 4.
Alekseev, S.V., Vorontsov, I.M., Nezhentsev, M.V., et al, Hygienic and Clinical Problems of the Childhood Ecology, Vestn. Ross. Akad. Med. Nauk, 1993, no. 5, p. 15.
Solntsev, A.A., Adaptation of Children to Microsocial Conditions, in Sovetskaya pediatriy (Soviet Pediatry), Moscow: Meditsina, 1989, p. 107.
Serdyukovskaya, G.N. and Chur’yanova, M.N., Methodology of Prenatal Diagnostics, Vestn. Ross. Akad. Med. Nauk, 1995, no. 7, p. 59.
Lebkova, N.P. Modern Concepts of Intracellular Mechanisms of Energy Homeostasis in Health and Disease, Vestn. Ross. Akad. Med. Nauk, 2000, no. 9, p. 16.
Meerson, F.Z., Adaptatsiya, stress i profilaktika (Adaptation, Stress, and Prophylaxis), Moscow: Nauka, 1981.
Suga, H., Ventricular Energetics, Physiol. Rev., 1990, vol. 70, no. 2, p. 247.
Baevskii, R.M., Kirillov, O.N., and Kletskin, S.Z., Matematicheskii analiz serdechnogo ritma pri stresse (Mathematical Analysis of Cardiac Rhythm in Stress), Moscow: Nauka, 1984.
Baevskii, R.M. and Berseneva, A.P. Otsenka adaptivnykh vozmozhnostei organizma i risk razvitiya zabolevanii (Assessment of Adaptive Abilities of the Body and the Risk of Diseases), Moscow: Meditsina, 1997.
Nartsissov, R.P. Diagnosticheskie i prognosticheskie vozmozhnosti tsitokhimii v pediatrii (Diagnostic and Prognostic Potential of Cytochemistry in Pediatrics), Moscow: Nauchn. Tsentr Zdor. Detstva Ross. Akad. Med. Nauk, 1997.
Vegetativnye rasstroistva: klinika, lechenie, diagnostika (Autonomic Disorders: Clinics, Therapy, and Diagnostics), Vein, A.M., Ed., Moscow: Med. Inform., 2000.
Nozdrachev, A.D. and Shcherbatykh, Yu.V., Modern Methods of Functional Studies of the Autonomic Nervous System, Fiziol. Chel., 2001, vol. 27, no. 6, p. 95 [Hum. Physiol. (Engl. Transl.), 2001, vol. 27, no. 6, p. 732].
Oskolkova, M.K., Funktsional’nye metody issledovaniya sistemy krovoobrashcheniya u detei (Functional Methods of Examination of the Cardiovascular System in Children), Moscow: Meditsina, 1988.
Nartisissov, R.P., Quantitative Cytochemistry of Human Lymphocytic Dehydrogenases with p-Nitrotetrazolium Violet, Arkh. Anat. Gistol. Embriol., 1969, vol. 56, no. 5, p. 85.
Kondrashova, M.N., Grigorenko, E.V., Babskii, A.M., et al., Homeostasis of Physiological Functions at the Mitochondrial Level, in Molekulyarnye mekhanizmy kletochnogo gomeostaza (Molecular Mechanisms of Cell Homeostasis), Novosibirsk: Nauka, 1987, p. 40.
Nartsissov, R.P., Prognostic Potential of Clinical Cytochemistry, in Sovetskaya pediatriya (Soviet Pediatrics), Moscow: Meditsina, 1984, p. 267.
Galeev, A.R., Igisheva, L.N., and Kazin, E.M., Heart Rate Variability in Healthy Six-to Sixteen-Year-Old Children, Fiziol. Chel., 2002, vol. 28, no. 5, p. 54 [Hum. Physiol. (Engl. Transl.), 2002, vol. 28, no. 4, p. 428].
Sokolova, O.I., Khaspekova, N.B., Chechel’nitskaya, S.M., et al., Heterogeneity on Autonomic Regulatory Mechanisms in Healthy Children, Shk. Zdor., 2000, vol. 7, no. 1, p. 90.
Davidenko, N.M., Problemy ekologii neftegazonosnykh i gornodobyvayushchikh regionov Severa Rossii (Ecological Problems of Oil-, Gas-, and Mineral Resource-Bearing Regions of Northern Russia), Novosibirsk: Nauka, 1998.
Ekologicheskoe sostoyanie, ispol’zovanie resursov, okhrana okruzhayushchei sredy Tyumenskoi oblasti (Ecological State, Use of Resources, and Preservation of the Environment in the Tyumen’ Oblast of Russia), Tyumen’: TOKOOS, 1997.
Author information
Authors and Affiliations
Additional information
Original Russian Text © A.N. Poborskii, 2007, published in Fiziologiya Cheloveka, 2007, Vol. 33, No. 1, pp. 55–62.
Rights and permissions
About this article
Cite this article
Poborskii, A.N. Autonomic regulation and cytochemical status of lymphocytes in children at the beginning of school education. Hum Physiol 33, 46–52 (2007). https://doi.org/10.1134/S0362119707010070
Received:
Issue Date:
DOI: https://doi.org/10.1134/S0362119707010070