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Plasticity of cortical structures under the conditions of neurological deficit accompanied by a disorder of hand movement: Modern approaches to rehabilitation

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Reorganization of cortical structures under the conditions of neurological deficit is an important interdisciplinary problem. This problem closely unites neurologists, physiologists, and mathematicians, which makes it possible to develop rehabilitation measures taking into account individual features. Fine hand movements under the conditions of motor pathology are an ideal model for investigation of neuroplasticity.

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References

  1. Gusev, E.I. and Kamchatov, P.R., Plasticity of the Nervous System, Zh. Nevrol. Psikhiatr. im. S.S. Korsakova, 2004, vol. 104, no. 3, p. 73.

    PubMed  CAS  Google Scholar 

  2. Freund, H.-J., Jeannerod, M., Hallett, M., and Leiguarda, R., Higher-Order Motor Disorders, NY: Oxford Univ. Press, 2005.

    Google Scholar 

  3. Johansson, B.B., Brain Plasticity in Health and Disease, Keio J. Med., 2004, vol. 53, no. 4, p. 231.

    Article  PubMed  Google Scholar 

  4. Mano, Y., Chuma, T., and Watanabe, I., Cortical Reorganization in Training, J. Electromyogr. Kinesiol., 2003, vol. 13, no. 1, p. 57.

    Article  PubMed  CAS  Google Scholar 

  5. Ziemann, U., Muellbacher, W., Hallett, M., and Cohen, L.G., Modulation of Practice-Dependent Plasticity in Human Motor Cortex, Brain, 2001, vol. 124, no. 6, p. 1171.

    Article  PubMed  CAS  Google Scholar 

  6. Damulin, I.V., Principles of Rehabilitation of Patients after Stroke, Sprav. Prakt. Vracha, 2003, vol. 3, no. 2, p. 21.

    Google Scholar 

  7. Butefisch, C.M., Plasticity in the Human Cerebral Cortex: Lessons from the Normal Brain and from Stroke, Neuroscientist, 2004, vol. 10, no. 2, p. 163.

    Article  PubMed  Google Scholar 

  8. Classen, J., Focal Hand Dystonia: A Disorder of Neuroplasticity?, Brain, 2003, vol. 126, no. 12, p. 2571.

    Article  PubMed  Google Scholar 

  9. Elbert, T. and Rockstroh, B., Reorganization of Human Cerebral Cortex: The Range of Changes Following Use and Injury, Neuroscientist, 2004, vol. 10, no. 2, p. 129.

    Article  PubMed  Google Scholar 

  10. Ashby, W.R., Design for a Brain. The Origin of Adaptive Behaviour, London: Chapman and Hall, 1960. Translated under the title Konstruktsiya mozga, Moscow: Izd. Inostrannoi Literatury, 1962.

    Google Scholar 

  11. Johansson, B.B., Brain Plasticity and Stroke Rehabilitation. The Willis Lecture, Stroke, 2000, vol. 31, p. 223.

    PubMed  CAS  Google Scholar 

  12. Berlucchi, G., The Origin of the Term Plasticity in the Neurosciences: Ernesto Lugaro and Chemical Synaptic Transmission, J. Hist. Neurosci., 2002, vol. 11, p. 305.

    Article  PubMed  Google Scholar 

  13. Nudo, R.J., Returning the Misfiring Brain, Proc. Natl. Acad. Sci. USA, 2003, vol. 100, no. 13, p. 7425.

    Article  PubMed  CAS  Google Scholar 

  14. Candia, V., Wienbruch, C., Elbert, T., et al., Effective Behavioral Treatment of Focal Hand Dystonia in Musicians Alters Somatosensory Cortical Organization, Proc. Natl. Acad. Sci. USA, 2003, vol. 100, p. 7942.

    Article  PubMed  CAS  Google Scholar 

  15. Byl, N.N., Roderick, J., Mohamed, O. et al., Effectiveness of Sensory and Motor Rehabilitation of the Upper Limb Following the Principles of Neuroplasticity: Patient Stabile Poststroke, Neurorehabil. Neural Repair, 2003, vol. 17, no. 3, p. 176.

    Article  PubMed  Google Scholar 

  16. Byl, N.N., Hagarajan, S.S., Merzenich, M.M., et al., Correlation of Clinical Neuromusculoskeletal and Central Somatosensory Performance: Variability in Controls and Patients with Severe and Mild Focal Hand Dystonia, Neurol. Plast., 2002, vol. 9, no. 3, p. 177.

    Google Scholar 

  17. Byl, N.N., Merzenich, M.M., and Jenkins, W.M., A Primate Genesis Model of Focal Dystonia and Repetitive Stain Injury: Learning-Induced Dedifferentiation of the Representation of the Hand in the Primary Somatosensory Cortex in Adult Monkeys, Neurology, 1996, vol. 47, p. 508.

    PubMed  CAS  Google Scholar 

  18. Sawaki, L., Cohen, L.G., Classen, J., et al., Enhancement of Use-Dependent Plasticity by D-amphetamine, Neurology, 2002, vol. 59, p. 1262.

    CAS  Google Scholar 

  19. Derakdzhshan, I., Why Do Movements of Subdominant Hand Produce Bilateral Activation of the Cortex in Emission neurovisualization?, Stroke (Russian edition), 2004, no. 1, p. 101.

  20. Shimizu, T., Hosaki, A., Hino, T., et al., Motor Cortical Disinhibition in the Unaffected Hemisphere after Unilateral Cortical Stroke, Brain, 2002, vol. 125, no. 8, p. 1896.

    Article  PubMed  Google Scholar 

  21. Bonifer, N., Anderson, K.M., Application of Constraint-Induced Movement Therapy for an Individual with Severe Chronic Upper-Extremity Hemiplegia, Phys. Ther., 2003, vol. 83, no. 4, p.384.

    PubMed  Google Scholar 

  22. Johansen-Berg, H., Rushworth, M.F., Bogdanovic, M.D., et al., The Role of the Ipsilateral Premotor Cortex in Hand Movement after Stroke, Proc. Natl. Acad. Sci. USA, 2002, vol. 99, no. 22, p. 14518.

    Article  PubMed  CAS  Google Scholar 

  23. Plautz, E.J., Barbay, S., Frost, S.B., et al., Post-Infarct Cortical Plasticity and Behavioral Recovery Using Concurrent Cortical Stimulation and Rehabilitative Training: A Feasibility Study in Primates, Neurol. Res., 2003, vol. 25, no. 8, p. 801.

    Article  PubMed  Google Scholar 

  24. Papathanasion, I., Filipovic, S.R., Whurr, R., et al., Plasticity of Motor Cortex Excitability by Rehabilitation Therapy for Writing, Neurology, 2003, vol. 61, no. 7, p. 977.

    Google Scholar 

  25. Liepert, J., Miltner, W.H., Bauder, H., et al., Motor Cortex Plasticity during Constraint-Induced Movement Therapy in Stroke Patients, Neurosci. Lett., 1998, vol. 250, no. 1, p. 5.

    Article  PubMed  CAS  Google Scholar 

  26. Liepert, J., Bauder, H., Miltner, W.H.R., et al., Treatment-Induced Cortical Reorganization after Stroke in Humans, Stroke, 2000, vol. 31, p. 1210.

    PubMed  CAS  Google Scholar 

  27. Calverley, R.K. and Jones, D.G., Contributions of Dendritic Spines and Performed Synapses to synaptic plasticity, Brain Res. Brain Res. Rev., 1990, vol. 15, p. 215.

    Article  PubMed  CAS  Google Scholar 

  28. Ioffe, M.E., Brain Mechanisms of the New Movements Formation in Learning: Evolution of Classical Views, Zh. Vyssh. Nerv. Deyat., 2003, vol. 53, no. 1, p. 5.

    CAS  Google Scholar 

  29. Ioffe, M.E., Plasticity of the Motor Brain Structures and Motor Learning, in Materialy III Vserossiiskoi s mezhdunarodnym uchastiem shkoly-konferentsii po fiziologii myshts i myshechnoi deyatel’nossty, posvyashchennoi 250-letiyu MGU im. M.V.Lomonosova (Proc. All-Russian, with International Participation, School/Conference on the Physiology of Muscles and Muscle Activity, Dedicated to the 250th Anniversary of Lomonosov State University, Moscow), 2005, p. 48.

  30. Moore, Ch.E.G. and Schady, W. Investigation of the Functional Correlates of Reorganization within the Human Somatosensory Cortex, Brain, 2000, vol. 123, no. 8, p. 1883.

    Article  PubMed  Google Scholar 

  31. Shavlovskaya, O.A., Orlova, O.R., and Golubev, V.L., Phenomenon of Paradoxical Kinesias in Writer’s Cramp, Zh. Nevrol. Psikhiatr. im. Korsakova, 2005, no. 9, p. 10.

  32. Gusev, E.I., Gehkt, A.B., Gaptov, V.B., Tikhopoi, E.V., Rehabilitation in Neurology. A Text-Book, Moscow, 2000

  33. Gusev, E.I., Grigor’ev, A.I., Kozlovskaya, I.B., and Gekht, A.B., Treatment and Rehabilitation of Poststroke Patients-Novel Methodological Possibilities, in Tezisy dokladov Rossiiskogo Mezhdunarodnogo kongressa: tserebro-vaskulyarnaya patologiya i insul’t (Abstracts of Russian International Congress: Cerebrovascular Pathology and Stroke), 22–24 September, 2003, Zh. Nevrol. Psikhiatr. im. S.S. Korsakova, 2003, no. 9, suppl., p. 187.

  34. Roder, B., Stock, O., Bien, S., et al., Speech Processing Activates Visual Cortex in Congenitally Blind Humans, Eur. J. Neurosci., 2002, vol. 16, p. 930.

    Article  PubMed  Google Scholar 

  35. Marshall, R.S., Perera, G.M., Lazar, R.M., et al., Evolution of Cortical Activation during Recovery from Corticospinal Tract Infarction, Stroke, 2000, vol. 31, p. 656.

    PubMed  CAS  Google Scholar 

  36. Buhmann, C., Gorsler, A., Bäumer, T., et al., Abnormal Excitability of Premotor-Motor Connections in de Novo Parkinson’s Disease, Brain, 2004, vol. 127, no. 12, p. 2732.

    Article  PubMed  CAS  Google Scholar 

  37. Morgen, K., Kadom, N., Sawaki, L., et al., Training-Dependent Plasticity in Patients with Multiple Sclerosis, Brain, 2004, vol. 127, no. 11, p. 2506.

    Article  PubMed  Google Scholar 

  38. Jacobs, B., Schall, M., and Scheibel, A., A Quantitative Dendrites Analysis of Wernicke’s Area. II. Gender, Hemispheric, and Environmental Factors, J. Comp. Neurol., 1993, vol. 237, p. 97.

    Article  Google Scholar 

  39. Duus, P., Topicheskii diagnoz v nevrologii. Anatomiya. Fiziologiya. Klinika (Topical Diagnosis in Neurology. Anatomy. Physiology. Clinics), Moscow: Vazar-Ferro, 1995, p. 304.

    Google Scholar 

  40. Hertz-Pannier, L., Chiron, C., Jambaqué, I., et al., Plasticity for Language in a Child’s Non-dominant Hemisphere. A pre-and Postsurgery fMRI Study, Brain, 2002, vol. 125, no. 2, p. 361.

    Article  PubMed  Google Scholar 

  41. Macdonell, R.A.L., Jackson, G.D., Curatolo, J.M., et al., Motor Cortex Localization Using Functional MRI and Trasncranial Magnetic Stimulation, Neurology, 1999, vol. 53, p. 1462.

    PubMed  CAS  Google Scholar 

  42. Nikitin, S.S. and Kurenkov, A.L., Mapping Cortical Motor Representation Using TMS, in Magnitnaya stimulyatsiya v diagnostike i lechenii boleznei nervnoi sistemy. Rukovodstvo dlya vrachei (Magnetic Stimulation in Diagnostics and Treatment of Diseases of Nervous System. A Handbook for Physicians), Moscow: Sashko, 2003, p. 125.

    Google Scholar 

  43. Gimranov, R.F., Transkranial’naya magnitnaya stimulyatsiya (Transcranial Magnetic Stimulation), Moscow: 2002.

  44. Cicinelli, P., Pasqualetti, P., Zaccagnini, M., et al., Interhemispheric Asymmetries of Motor Cortex Excitability in the Postacute Stroke Stage: A Paired-Pulse Transcranial Magnetic Stimulation Study, Stroke, 2003, vol. 34, no. 11, p. 2653.

    Article  PubMed  Google Scholar 

  45. Stefan, K., Kunesch, E., Cohen, L.G., et al., Induction of Plasticity in the Human Motor Cortex by Paired Associative Stimulation, Brain, 2000, vol. 123, no. 3, p. 572.

    Article  PubMed  Google Scholar 

  46. McKenzie, A.L., Nagarajan, S.S., Roberts, T.P., et al., Somatosensory Representation of the Digits abd Clinical Performance with Focal Hand Dystonia, Am. J. Phys. Med. Rehabil., 2003, vol. 82, no. 10, p. 737.

    Article  PubMed  CAS  Google Scholar 

  47. Candia, V., Elbert, T., Altenmuller, E., et al., Constraint-Induced Movement Therapy for Focal Hand Dystonia in Musicians, Lancet, 1999, vol. 353, p. 42.

    Article  PubMed  CAS  Google Scholar 

  48. Candia, V., Schafer, T., Taub, E., et al., Sensory Motor Returning: A behavioral Treatment for Focal Hand Dystonia of Pianists and Guitarists, Arch. Phys. Med. Rehabil, 2002, vol. 83, p. 1342.

    Article  PubMed  Google Scholar 

  49. Quatarone, A., Bagnato, S., Rizzo, V., et al., Abnormal Associative Plasticity of the Human Motor Cortex in Writer’s Cramp, Brain, 2003, vol. 126, no. 12, p. 2586.

    Article  Google Scholar 

  50. Rizzo, V., Quartarone, A., Bagnato, S., et al., Motor Imagery Impairment in Writer’s Cramp Patients, in Abstr. 8th International Congr. of Parkinson’s Disease and Movement Disorders, Rome, 2004, p. 281.

  51. Siebner, H.R., Tormos, J.M., Ceballos-Baumann, A.O., et al., Low-Frequency Repetitive Transcranial Magnetic Stimulation of the Motor Cortex in Writer’s Cramp, Neurology, 1999, vol. 52, p. 529.

    PubMed  CAS  Google Scholar 

  52. Thompson, M.L., Thikbroom, G.W., Sacco, C., et al., Changes in the Organization of Corticomotor Projection to the Hand in Writer’s Cramp, Mov. Disord., 1996, vol. 11,suppl. 1, p. 13.

    Google Scholar 

  53. Weise, D., Schramm, A., Stefan, K., et al., Disturbance of Associative Motor Cortical Plasticity in Focal Hand Dystonia, in Abstr. 8th International Congr. of Parkinson’s Disease and Movement Disorders, Rome, 2004, p. 236.

  54. Cincotta, M., Borgheresi, A., Balzini, L., et al., Separate Ipsilateral and Contralateral Corticospinal Projection in Congenital Mirror Movements: Neurophysiological Evidence and Significance for Motor Rehabilitation, Mov. Disord., 2003, vol. 18, no. 11, p. 1294

    Article  PubMed  Google Scholar 

  55. Borgheresi A., Cincotta, M., Balestrieri, F., et al., Involvement of the Right Dorsal Premotor Cortex (PMC) in Neural Control of Unimanual Movements: An Interference Approach Using Transcranial Magnetic Stimulation (TMS), in Abstr. 8th International Congr. of Parkinson’s Disease and Movement Disorders, Rome, 2004, p. 163.

  56. Schaechter, J.D., Kraft, E., Hilliard, T.S., et al., Motor Recovery and Cortical Reorganization after Constraint-Induced Movement Therapy in Stroke Patients: A Preliminary Study, Neurorehabil. Neural Repair, 2002, vol. 16, no. 4, p. 326.

    Article  PubMed  Google Scholar 

  57. Gekht, A.B., Treatment of Stroke Patients in Rehabilitation Period, Cons. Med., 2000, vol. 2, no. 12, p. 1156.

    Google Scholar 

  58. Taub, E., Miller, N.E., Novack, T.A., et al., Technique to Improve Chronic Motor Deficit after Stroke, Arch. Phys. Med Rehabil., 1993, vol. 74, no. 4, p. 347.

    PubMed  CAS  Google Scholar 

  59. Grasso, R., Ivanenko, Y.P., Zago, M., et al., Distributed Plasticity of Locomotor Pattern Generators in Spinal Cord Injured Patients, Brain, 2004, vol. 127, no. 5, p. 1019.

    Article  PubMed  Google Scholar 

  60. Potekhin, L.D., Kinezioterapiya bol’nykh so spinal’noi paraplegiei. Uchebnoe posobie dlya vrachei, metodistov i instruktorov lechebnoi fizkulrury, vrachei-fizioterapevtov (Kinesthesiological Therapy of Patients with Spinal Paraplegia. A Handbook for Physicians, Methodists and Instructors of Exercise Therapy, and Physiatrists), Petrov, K.B., Ed., Novokuznetsk, 2002.

  61. Young, W., The Effects of Intensive Training on Motor Recovery, http://carecure.rutgers.edu

  62. Leont’ev, M.A. and Malashenko, M.M., Dvigatel’naya reabilitatsiya invalidov s narusheniem dvigatel’noi lokomotornoi funktsii vsledstvie paralichei i parezov. Metodicheskie rekomendatsii dlya vrachei, metodistov i instruktorov LFK (Motor Rehabilitation of Invalid Patients with Locomotion Disorders as a Result of Paraplegias or Pareses: Methodological Recommendations for Physicians and Physiatrists), Novokuznetsk, 2002.

  63. Taub, E., Crago, J.E., Burgio, L.D., et al., An Operant Approach to Rehabilitation Medicine: Overcoming Learned Nonuse by Shaping, J. Exp. Anal. Behav., 1994, vol. 61, no. 2, p. 281.

    Article  PubMed  CAS  Google Scholar 

  64. Kopp, B., Kunkel, A., Muhlnickel, W., et al., Plasticity in the Motor System Related to Therapy-Induced Improvement of Movement after Stroke, Neuroreport, 1999, vol. 10, no. 4, p. 807.

    PubMed  CAS  Google Scholar 

  65. Taub, E., Uswatte, G., and Pidikiti, R., Constraint-Induced Movement Therapy: A New Family of Techniques with Broad Application to Physical Rehabilitation-A Clinical Review, J. Rehabil. Res. Dev., 1999, vol. 36, no. 3, p. 237.

    PubMed  CAS  Google Scholar 

  66. Taub, E. and Uswatte, G., Constraint-Induced Movement Therapy: Bridging from the Primate Laboratory to the Stroke Rehabilitation Laboratory, J. Rehabil. Med., 2003, vol. 41,suppl., p. 34.

    Article  PubMed  Google Scholar 

  67. Taub, E., Ramey, S.L., DeLuca, S., and Echols, K., Efficacy of Constraint-Induced Movement Therapy for Children with Cerebral Palsy with Asymmetric Motor Impairment, Pediatrics, 2004, vol. 113, no. 2, p. 305.

    Article  PubMed  Google Scholar 

  68. Wissel, J. and Pullman, S.L., Task-Specific Dystonia and Occupational Cramps, in The Movement Disorders Society’s 6’th International Congress of Parkinson’s Disease and Movement Disorders, Barselona, 2000, p. 1.

  69. Zeuner, K.E., Bara-Jimenez, W., Noguchi, P.S., et al., Sensory Training for Patient with Focal Hand Dystonia, Ann. Neurol., 2002, vol. 51, p. 593.

    Article  PubMed  Google Scholar 

  70. Carey, L.M., Abbot, D.F., Puce, A., et al., Reemergence of Activation with Poststroke Somatosensory Recovery: A Serial fMRI Study, Neurology, 2002, vol. 59, p. 749.

    PubMed  CAS  Google Scholar 

  71. Hallett, M., Plasticity of the Human Motor Cortex and Recovery from Stroke, Brain Res. Rev., 2001, vol. 36, p. 169.

    Article  PubMed  CAS  Google Scholar 

  72. Nelles, G., Spiekermann, G., Jueptner, M., et al., Reorganization of Sensory and Motor Systems in Hemiplegic Stroke Patients: A Positron Emission Tomography Study, Stroke, 1999, vol. 30, p. 1510.

    PubMed  CAS  Google Scholar 

  73. Dobkin, B.H. and Thompson, A.J., Principles of Neurological Rehabilitation, Neurology in Clinical Practice, Bradley et al., Eds., Butterworth-Neinemann, 2000, p. 518.

  74. Muellbacher, W., Artner, C., and Mamoli, B., The Role of the Intact Hemisphere in Recovery of Midline Muscles after Recent Monohemispheric Stroke, J. Neurol., 1999, vol. 246, p. 250.

    Article  PubMed  CAS  Google Scholar 

  75. Weiller, C. and Rijntjes, M., Learning, Plasticity, and Recovery in the Central Nervous System, Exp. Brain Res., 1999, vol. 128, p. 134.

    Article  PubMed  CAS  Google Scholar 

  76. Hesse, S., Schulte-Tigges, G., Kinrad, M., et al., Robot-Assisted Arm Trainer for the Passive and Active Practice of Bilateral Forearm and Wrist Movements in Hemiparetic Subjects, Arch. Phys. Med. Rehabil., 2003, vol. 84, no. 6, p. 915.

    Article  PubMed  Google Scholar 

  77. Stinear, J.W. and Biblow, W.D., Modulation of Human Cervical Premotoneurons During Bilateral Voluntary Contraction of Upper-Limb muscles, Muscle Nerve, 2004, vol. 29, no. 4, p. 506.

    Article  PubMed  Google Scholar 

  78. Godbout, C.J. and Johns, J.S., Stroke Motor Impairment, Physical Medicine and Rehabilitation, Potter, P.J. et al., Eds., London: e-Medicine, 2002, p. 432.

    Google Scholar 

  79. Stienear, C.M., Motor Imagery of Phasic Thumb Abduction Temporally and Spatially Modulates Corticospinal Excitability, Clin. Neurophysiol., 2003, vol. 114, no. 5, p. 909.

    Article  Google Scholar 

  80. Stevens, J. and Stoykov, M.E., Using Imagery in the Rehabilitation of Hemiparesis, Arch. Phys. Med. Rehabil., 2003, vol. 84, no. 7, p. 1090.

    Article  PubMed  Google Scholar 

  81. Golubev, V.L., Levin, Ya.I., and Vein, A.M., Treatment of Parkinsonism, in Bolezn’ Parkinsona i sindrom parkinsonisma (Parkinson’s Disease and Parkinson’s Syndrome), Moscow: Medpress, 1999, p. 349.

    Google Scholar 

  82. Nicolelis, M.A. and Chapin, J.K., Controlling Robots with the Mind, Sci. Am., 2002, vol. 287, no. 4, p. 46.

    Article  PubMed  Google Scholar 

  83. Donoghue, J., Connecting Cortex to Machines: Recent Advances in Brain Interfaces, Nat. Neurosci., 2002, vol. 5, p. 1085.

    Article  PubMed  CAS  Google Scholar 

  84. Laibow, R. Medical Applications of Neurobiofeedback, Introduction to Quantitative EEG and Neurofeedback, Evans J.R. and Abarbanel, A., Eds., New York: Academic, 1999, p. 83.

    Google Scholar 

  85. Musco, M., Weiller, C., Kiebel, St., et al., Training-Induced Brain Plasticity in Aphasia, Brain, 1999, vol. 122, no. 9, p. 1781.

    Article  Google Scholar 

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Original Russian Text © O.A. Shavlovskaya, 2006, published in Fiziologiya Cheloveka, 2006, Vol. 32, No. 6, pp. 119–125.

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Shavlovskaya, O.A. Plasticity of cortical structures under the conditions of neurological deficit accompanied by a disorder of hand movement: Modern approaches to rehabilitation. Hum Physiol 32, 735–741 (2006). https://doi.org/10.1134/S0362119706060193

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