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Adaptive changes in temperature sensitivity in humans under the conditions of cold, heat, and prolonged exercise

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Abstract

In humans adapted for a long time to various conditions—cold, heat, and physical exercise—differently directed changes in temperature sensitivity are observed. During long-term adaptation of humans to cold, a decrease in cold sensitivity is observed. Vice versa, in humans adapted to a hot climate, sensitivity to heat is decreased. Prolonged physical exercise does not change the sensitivity to heat but considerably increases the sensitivity to cold. Some mechanisms and the role of noradrenaline, the postganglionic neurotransmitter of the sympathetic nervous system, in the adaptive processes of a change in temperature sensitivity are considered.

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References

  1. Bruck, K. and Zeisberger, E., Adaptive Changes in Thermoregulation and Their Neuropharmacological Basis, Pharmacol. Ther., 1984, vol. 35, p. 163.

    Article  Google Scholar 

  2. Kozyreva, T.V. and Verkhoglyad, L.A., Adaptation to Cold and the Structure of the Thermoregulatory Response during Slow and Rapid Cooling, Ross. Fiziol. Zh., 1997, vol. 83, nos. 11–12, p. 135.

    CAS  Google Scholar 

  3. Blix, M., Exerimentalle beitrage zur der frage uber die spezifische energie der hautnerven, J. Zool. Biol., 1884, vol. 20, p. 141.

    Google Scholar 

  4. Kenshalo, D.R. and Galegos, E.F., Multiple Temperature-Sensitive Spots Innervated by Single Nerve Fibers, Science, 1967, vol. 158, p. 1064.

    Article  PubMed  CAS  Google Scholar 

  5. Hensel, H. and Anders, K.H., Structure and Function of Cold Receptors, Pflug. Arch., 1974, vol. 352, p. 1.

    Article  CAS  Google Scholar 

  6. Kenshalo, D.R., Cutaneous Temperature Sensitivity, in Foundation of Sensory Science, Dawson, W.W. and Enock, J.M., Eds., Berlin: Springer, 1984.

    Google Scholar 

  7. Kozyreva, T.V. and Yakimenko, M.A., On Temperature Sensitivity to Cold in Humans, Fiziol. Zh. SSSR, 1978, vol. 62, no. 2, p. 220.

    Google Scholar 

  8. Kozyreva, T.V. and Yakimenkok, M.A., The Effects of Adaptation to a Warm Climate on the State of Thermoreceptors, Fiziol. Chel., 1984, vol. 10, no. 1, p. 117.

    CAS  Google Scholar 

  9. Yakimenko, M.A., Tkachenko, E.Ya, Divert, V.E., and Fil’ko, O.A., Some Indices of the Thermoregulation System in Humans at the Body Adaptation to Cold under the Conditions of the Polar Region, Fiziol. Chel., 1979, vol. 5, no. 5, p. 931.

    Google Scholar 

  10. Yakimenko, M.A., Long-Term Adaptation to Cold in Humans and Animals, in Fiziologiya termoregulyatsii. Rukovodstvo po fiziologii (Physiology of Thermoregulation: Handbook of Physiology), Leningrad: Nauka, 1984, p. 223.

    Google Scholar 

  11. Kozyreva, T.V. and Simonova, T.G., The Modulating Effect of Peripheral Receptors on Human Respiration, Vestn. Ross. Akad. Med. Nauk, 1998, no. 9, p. 14.

  12. Slonim, A.D., Treatise on Physiological Adaptations, in Ekologicheskaya fizologiya zhivotnykh (Ecological Physiology of Animals), Leningrad: Nauka, 1979, Part 1, p. 79.

    Google Scholar 

  13. Bazhenov, Yu.I., Termogenezis i myshechnaya deyatel’nost’ pri adaptatsii k kholodu (Thermogenesis and Muscular Activity at Adaptation to Cold), Leningrad: Nauka, 1981.

    Google Scholar 

  14. Kozyreva, T.V. and Yakimenko, M.A., The Effects of Adaptation to Cold on the Impulse Activity of Skin Thermoreceptors, Fiziol. Zh. SSSR, 1979, vol. 65, no. 11, p. 1598.

    PubMed  CAS  Google Scholar 

  15. Hensel, H. and Schafer, K., Static and Dynamic Activity of Cold Receptors in Cats After Long-Term Exposure to Various Temperatures, Pflug. Arch., 1982, vol. 392, p. 291.

    Article  CAS  Google Scholar 

  16. Kozyreva, T.V., Modulation of the Functional Properties of Skin Thermoreceptors, Neirofiziologiya, 1992, vol. 24, no. 5, p. 542.

    CAS  Google Scholar 

  17. Kozyreva, T.V., Tkachenko, E.Ya., and Simonova, T.G., Functional Changes during Adaptation to Cold, Usp. Fiziol. Nauk, 2003, vol. 34, no. 2, p. 94.

    Google Scholar 

  18. Depocas, F., Behrens, W.A., and Foster, D.O., Noradrenaline-Induced Calorigenesis in Warm-and in Cold-Acclimated Rats: The Interrelation of Dose of Noradrenaline, Its Concentration in Arterial Plasma, and Calorigenic Response, Can. J. Physiol. Pharm., 1978, vol. 56, p. 168.

    CAS  Google Scholar 

  19. Barrand, M.A., Dauncey, M.J., and Ingram, D.L., Changes in Plasma Noradrenaline and Adrenaline Associated with Central and Peripheral Thermal Stimuli in the Pig, J. Physiol., 1981, vol. 316, p. 139.

    PubMed  CAS  Google Scholar 

  20. Kozyreva, T.V., Tkachenko, E.Ya, Kozaruk, V.P., et al., Effects of Slow and Rapid Cooling on Catechlomine Concentration in Arterial Plasma and Skin, Am. J. Physiol. Regul. Integr., 1999, vol. 45, p. R1668.

    Google Scholar 

  21. LeBlanc, J., Adaptation of Man to Cold, in Strategies in Cold: Natural Torpidity and Thermogenesis, Wang, L.C.H. and Hudson, J.W., Eds., New York: Academic Press, 1978, p. 695.

    Google Scholar 

  22. Kozyreva, T.V. and Yakimenko, M.A., Sensitivity of Skin Cold Receptors to Noradrenaline in Control and Cold-Adapted Rats, Fiziol. Zh. SSSR, 1984, vol. 70, no. 3, p. 331.

    PubMed  CAS  Google Scholar 

  23. Kozyreva, T.V. and Pierau, F.K., Effects of Cold Adaptation and Noradrenaline on Thermosensitivity of Rat Hypothalamic Neurons Studied in Vitro, Neurophysiology, 1994, vol. 26, p. 171.

    CAS  Google Scholar 

  24. Kozyreva, T.V., Two Periods in the Response of the Skin Cold Receptors to Intravenous Infusion of Noradrenaline, Ann. New York Sci., 1997, vol. 813, p. 176.

    CAS  Google Scholar 

  25. Kozyreva, T.V., Activity of Central and Peripheral Thermoreceptors during Long-Term Adaptation to Cold and the Effects of Noradrenaline (Comparative Analysis), in Organizm i Sreda (Body and the Environment), Trufakin, V.A. and Shoshenko, K.A., Eds., Novosibirsk: SO RAMN, 2003, p. 81.

    Google Scholar 

  26. Kozyreva, T.V., Tkachenko, E.Ya, Eliseeva, L.S., et al., A Possible Mechanism for Noradrenaline Involvement in the Effector Responses to Cold Exposure, J. Thermal Biol., 2001, vol. 26, no. 5, p. 505.

    Article  CAS  Google Scholar 

  27. Clapham, D.E., Runnels, L.W., and Strubing, C., The TRP Ion Channel Family, Nat. Rev. Neurosci., 2001, vol. 2, p. 387.

    Article  PubMed  CAS  Google Scholar 

  28. McKemy, Neuhasser, W.M., and Julius, D., Identification of a Cold Receptor Reveals a General Role for TRP Channels in Thermosensation, Nature, 2002, vol. 416, p. 52.

    Article  PubMed  CAS  Google Scholar 

  29. Reid, G., Babes, A., and Plarteau, F., A Cold-and Menthol-Activated Current in Rat Dorsal Root Ganglion Neurons: Properties and Role in Cold Transduction, J. Physiol., 2002, vol. 545, no. 2. p. 595.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Institute of Physiology, Siberian Division, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia

    T. V. Kozyreva

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Original Russian Text © T.V. Kozyreva, 2006, published in Fiziologiya Cheloveka, 2006, Vol. 32, No. 6, pp. 103–108.

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Kozyreva, T.V. Adaptive changes in temperature sensitivity in humans under the conditions of cold, heat, and prolonged exercise. Hum Physiol 32, 721–725 (2006). https://doi.org/10.1134/S0362119706060168

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  • DOI: https://doi.org/10.1134/S0362119706060168

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