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Physiological and ethnogenetic risk factors for cardiovascular thrombosis

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Abstract

An analysis of publications on the polymorphism of enzymes, receptors, and other systems of lipid and lipoprotein metabolism critical for the formation of vascular lipoprotein plaques and thrombi revealed the importance of certain genetic factors for the development of cardiovascular disorders. However, because of the polygenic nature of these disorders, the assessment of the corresponding hereditary risk factors requires multivariablecorrelation analysis. Population studies show that the polymorphism of individual genes manifests itself in the difference in incidence rates between ethnic groups.

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  1. Center of Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences, Moscow, 117972, Russia

    V. A. Sukhanov & L. A. Piruzyan

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Original Russian Text © V.A. Sukhanov, L.A. Piruzyan, 2006, published in Fiziologiya Cheloveka, 2006, Vol. 32, No. 3, pp. 98–110.

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Sukhanov, V.A., Piruzyan, L.A. Physiological and ethnogenetic risk factors for cardiovascular thrombosis. Hum Physiol 32, 334–345 (2006). https://doi.org/10.1134/S0362119706030145

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