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Influence of the Structure of Molecules of Derivatives of 1,2,4-Triazole and 1,2,4-Triazine on Chromatographic Retention Under Conditions of Reversed Phase HPLC

  • PHYSICAL CHEMISTRY OF SEPARATION PROCESSES. CHROMATOGRAPHY
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Abstract

The dependence of the chromatographic retention of 1,2,4-triazine and 1,2,4-triazole derivatives from water–acetonitrile solutions over octadecyl silica on the structure of sorbate molecules is studied. The effect the physicochemical parameters and topology of heterocycle molecules have on the retention characteristics under RP HPLC conditions is analyzed.

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Authors and Affiliations

  1. Samara National Research University, 443086, Samara, Russia

    I. N. Karaseva, M. O. Karasev, O. N. Nechaeva & S. V. Kurbatova

Authors
  1. I. N. Karaseva
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  2. M. O. Karasev
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  3. O. N. Nechaeva
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  4. S. V. Kurbatova
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Correspondence to S. V. Kurbatova.

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Translated by V. Kudrinskaya

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Karaseva, I.N., Karasev, M.O., Nechaeva, O.N. et al. Influence of the Structure of Molecules of Derivatives of 1,2,4-Triazole and 1,2,4-Triazine on Chromatographic Retention Under Conditions of Reversed Phase HPLC. Russ. J. Phys. Chem. 92, 1406–1412 (2018). https://doi.org/10.1134/S0036024418070142

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  • DOI: https://doi.org/10.1134/S0036024418070142

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