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Stabilizing selenium nanoparticles with chymotrypsin: The effect of pH and nanoparticle-enzyme concentration ratios on the stability of nanocomplexes

  • Physical Chemistry of Nanoclusters and Nanomaterials
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Abstract

Conditions of the formation of soluble chymotrypsin complexes with selenium nanoparticles are studied. It is established that the aggregative stability of the nanocomplexes is determined by their conditions of preparation, depending also on the medium pH and ratio of selenium: chymotrypsin concentration. It is shown that chymotrypsin has a “protective” effect due to its hydrophobic adsorption on the surface of selenium nanoparticles and hence the hydrophilization of their surfaces due to ionized groups of the protein.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, 199004, Russia

    L. N. Borovikova, A. V. Titova, N. A. Matveeva & O. A. Pisarev

Authors
  1. L. N. Borovikova
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  2. A. V. Titova
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  3. N. A. Matveeva
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  4. O. A. Pisarev
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Corresponding author

Correspondence to O. A. Pisarev.

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Original Russian Text © L.N. Borovikova, A.V. Titova, N.A. Matveeva, O.A. Pisarev, 2013, published in Zhurnal Fizicheskoi Khimii, 2013, Vol. 87, No. 6, pp. 1009–1012.

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Borovikova, L.N., Titova, A.V., Matveeva, N.A. et al. Stabilizing selenium nanoparticles with chymotrypsin: The effect of pH and nanoparticle-enzyme concentration ratios on the stability of nanocomplexes. Russ. J. Phys. Chem. 87, 998–1001 (2013). https://doi.org/10.1134/S0036024413060058

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  • DOI: https://doi.org/10.1134/S0036024413060058

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