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Assessing the antioxidant activity of certain drugs in oxidation of emulsions

  • Chemical Kinetics and Catalysis
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Abstract

The results from developing a kinetic model for testing water-soluble antioxidants by examining the micelle formation and oxidation kinetics of water-emulsion ethyl oleate and methyl linoleate substrates are presented. The optimum composition of the system, the catalyst, and the emulsifying agent are selected. The model is tested using standard, synthetic, and natural antioxidants. Criteria for evaluating the antioxidant’s efficiency are proposed. A more complex mechanism for the action of ionol is presented, along with the possibility of using it as an external standard. The high antioxidant activity of capoten and the manifestation of antioxidant properties by α-tocopherol under selected conditions are demonstrated.

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Correspondence to L. A. Zhuravleva.

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Original Russian Text © L.A. Zhuravleva, 2011, published in Zhurnal Fizicheskoi Khimii, 2011, Vol. 85, No. 7, pp. 1236–1240.

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Zhuravleva, L.A. Assessing the antioxidant activity of certain drugs in oxidation of emulsions. Russ. J. Phys. Chem. 85, 1130–1134 (2011). https://doi.org/10.1134/S0036024411070387

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  • DOI: https://doi.org/10.1134/S0036024411070387

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