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Structural and conformational characteristics of DNA complexes with polycations of different structure

  • Structure of Matter and Quantum Chemistry
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Abstract

The formation of DNA complexes with polycations of different structure (homopolymers: N,N-dimethylaminoethyl and methylsulfate salt of N,N,N-trimethylaminoethylmethacrylate, along with a copolymer of N,N-dimethylaminoethyl methacrylate with N-methacryloylaminoglucose) in water-salt solutions, was studied by the method of static and dynamic light scattering. It was shown that, depending on the value of ϕ = [mol polycation]/[mole of DNA], complexes of different structure are formed: in field ϕ < 6, they are dense and compact formations; when ϕ > 6 in the presence of a large excess of polycations, loose structures are formed. The extreme dependence of the molecular weight of formed supramolecular structures on the values of ϕ was established.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, 199004, Russia

    D. Yu. Ershov, A. I. Kipper, S. V. Valueva, O. V. Nazarova, Yu. I. Zolotov & E. F. Panarin

Authors
  1. D. Yu. Ershov
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  2. A. I. Kipper
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  3. S. V. Valueva
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  4. O. V. Nazarova
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  5. Yu. I. Zolotov
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  6. E. F. Panarin
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Corresponding author

Correspondence to A. I. Kipper.

Additional information

Original Russian Text © D.Yu. Ershov, A.I. Kipper, S.V. Valueva, O.V. Nazarova, Yu.I. Zolotov, E.F. Panarin, 2010, published in Zhurnal Fizicheskoi Khimii, 2010, Vol. 84, No. 5, pp. 932–935.

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Ershov, D.Y., Kipper, A.I., Valueva, S.V. et al. Structural and conformational characteristics of DNA complexes with polycations of different structure. Russ. J. Phys. Chem. 84, 831–834 (2010). https://doi.org/10.1134/S0036024410050213

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  • DOI: https://doi.org/10.1134/S0036024410050213

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