Abstract
The enthalpies of solution of sodium naproxene and dilution of its aqueous solutions were measured on an isoperibolic calorimeter at 293.15, 298.15, 303.15, 308.15, 313.15, and 318.15 K. The maximum content of the electrolyte was determined by its solubility at the given temperature (0.038–0.083 mol/kg solvent). The Pitzer model was used to obtain the virial coefficients for calculations of many excess thermodynamic properties of both solutions and their components. Changes in these characteristics depending on the concentration and temperature are considered.
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References
D. W. Scholer, K. E. C. Boettcher, and A. Schweizer, Am. J. Med. 80, 34 (1986).
A. Fini, G. Fazio, and G. Feroci, Int. J. Pharm. 126, 95 (1995).
F. Barbato, G. Caliendo, M. I. La Rotonda, et al., Quant. Struct.-Act. Relat. 5, 88 (1986).
A. Avdeef, Absorption and Drug Development: Solubility, Permeability, and Charge State (Wiley, Hoboken, NJ, 2003), p. 287.
K. S. Pitzer, J. Chem. Phys. 77(2), 268 (1973).
K. S. Pitzer, in Thermodynamic Modeling of Geological Materials: Minerals, Fluids and Melts, Ed. by I. S. E. Carmichael and H. P. Eugster, Vol. 17 of Reviews in Mineralogy (Mineralogical Society of America, Washington, D.C., 1987; Mir, Moscow, 1992).
L. F. Silvester and K. S. Pitzer, J. Phys. Chem. 81, 1822 (1977).
Y.-S. Kim, J. R. Mendez del Rio, and R. W. Rousseau, J. Pharm. Sci. 94, 1941 (2005).
N. G. Manin, G. L. Perlovich, A. N. Manin, and A. Fini, Zh. Fiz. Khim. 81(7), 1212 (2007) [Russ. J. Phys. Chem. A 81 (7), 1062 (2007)].
A. N. Kinchin, A. M. Kolker, and G. A. Krestov, Zh. Fiz. Khim. 60(3), 782 (1986).
Thermodynamic Properties of Pure Substances: A Handbook, Ed. by V. P. Glushko (Nauka, Moscow, 1982), Vol. 4, Part 1, p. 623 [in Russian].
V. A. Kobenin and A. N. Kazanskii, in Thermodynamic Properties of Solutions (Ivanovsk. Khim.-Tekhnol. Inst., Ivanovo, 1984), p. 3 [in Russian].
V. P. Vasil’ev, Thermodynamic Properties of Solutions of Electrolytes (Vysshaya shkola, Moscow, 1982) [in Russian].
R. H. Busey, H. F. Holmes, and R. E. Mesmer, J. Chem. Thermodyn. 16, 343 (1984).
J. E. Mayrath and R. H. Wood, J. Chem. Thermodyn. 15, 625 (1983).
R. A. Robinson and R. M. Stokes, Electrolyte Solutions: the Measurement and Interpretation of Conductance, Chemical Potential, and Diffusion in Solutions of Simple Electrolytes, 2nd ed. (Academic, New York, 1959; Inostrannaya Literatura, Moscow, 1963).
K. P. Mishchenko and G. M. Poltoratskii, Problems of Thermodynamics and Structure of Aqueous and Nonaqueous Solutions of Electrolytes (Khimiya, Leningrad, 1968) [in Russian].
N. G. Manin, A. V. Kustov, and V. P. Korolev, Zh. Fiz. Khim. 49(1), 120 (2004).
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Original Russian Text © N.G. Manin, A. Fini, G.L. Perlovich, 2009, published in Zhurnal Fizicheskoi Khimii, 2009, Vol. 83, No. 2, pp. 252–261.
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Manin, N.G., Fini, A. & Perlovich, G.L. A thermochemical study of aqueous solutions of sodium naproxene. Russ. J. Phys. Chem. 83, 187–196 (2009). https://doi.org/10.1134/S0036024409020083
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DOI: https://doi.org/10.1134/S0036024409020083