Abstract
A complex approach was proposed for early diagnosis of skin melanoma. The approach includes sequential examinations of skin lesions using several imaging systems. A focus is placed on the specifics of morphometry using clinical images of skin neoplasms, features of imaging systems, and main steps of automated image processing and image recognition to diagnose melanoma. Metrological features were described for the approach; errors of measuring the clinical parameters of skin neoplasms did not exceed the allowable error level. The approach was tested, and the sensitivity and specificity of the methods employed was found to be higher than 90%.
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REFERENCES
N. Eisemann, A. Waldmann, A. C. Geller, M. A. Weinstock, B. Volkmer, R. Greinert, E. W. Breitbart, and A. Katalinic, J. Invest. Dermatol. 134, 43 (2014). https://doi.org/10.1038/jid.2013.304
P. E. LeBoit, G. Burg, D. Weedon, and A. Sarasain, World Health Organization Classification of Tumours. Pathology and Genetics of Skin Tumours (IARC, Lyon, 2006).
W. R. Shaikh, M. Xiong, and M. A. Weinstock, Arch. Dermatol. 148, 30 (2012). https://doi.org/10.1001/archdermatol.2011.264
S. T. Chen, A. C. Geller, and H. Tsao, Curr. Dermatol. Rep. 2, 24 (2013). https://doi.org/10.1007/s13671-012-0035-5
V. Nikolaou and A. J. Stratigos, Br. J. Dermatol. 170, 11 (2014). https://doi.org/10.1111/bjd.12492
H. Tsao, J. M. Olazagasti, K. M. Cordoro, J. D. Brewer, S. C. Taylor, J. S. Bordeaux, M. M. Chren, A. J. Sober, C. Tegeler, R. Bhushan, and W. S. Begolka, J. Am. Acad. Dermatol. 72, 717 (2015). https://doi.org/10.1016/j.jaad.2015.01.025
R. L. Siegel, K. D. Miller, and A. Jemal, CA Cancer J. Clin. 66, 7 (2016). https://doi.org/10.3322/caac.21332
R. L. Siegel, K. D. Miller, and A. Jemal, CA Cancer J. Clin. 67, 7 (2017). https://doi.org/10.3322/caac.21387
L. Rahib, B. D. Smith, R. Aizenberg, A. B. Rosenzweig, J. M. Fleshman, and L. M. Matrisian, Cancer Res. 74, 2913 (2014). https://doi.org/10.1158/0008-5472.CAN-14-0155
O. M. Konopatskova and L. F. Zhandarova, in Proceedings of the All-Union Symposium,1990, p. 33.
J. E. Mayer, S. M. Swetter, T. Fu, and A. C. Geller, J. Am. Acad. Dermatol. 71, 599e1 (2014). https://doi.org/10.1016/j.jaad.2014.05.046
K. G. Kudrin, O. V. Matorin, and I. V. Reshetov, J. Phys.: Conf. Ser. 584, 012001 (2015). https://doi.org/10.1088/1742-6596/584/1/012001
A. Eggermont, A. Spatz, and C. Robert, Lancet 1, 816 (2014). https://doi.org/10.1016/S0140-6736(13)60802-8
P. Rubegni, M. Burroni, R. Perotti, M. Fimiani, L. Andreassi, G. Cevenini, and P. Barbini, J. Invest. Dermatol. 119, 471 (2002).
M. L. Bafounta, A. Beauchet, P. Aegerter, and P. Saiag, Arch. Dermatol. 137, 1343 (2001).
D. E. Cohen, O. P. Sangueza, E. Pass, and M. J. Stiller, Int. J. Dermatol. 32, 257 (1993). https://doi.org/10.1111/j.1365-4362.1993.tb04263.x
M. Bleve, P. Capra, F. Pavanetto, and P. Perugini, Dermatol. Res. Pract., 673706 (2012). https://doi.org/10.1155/2012/673706
L. V. Demidov, D. V. Sokolov, and I. V. Bulycheva, J. Blokhin Russ. Cancer Res. Center RAMS 18, 36 (2007).
H. Kittler, A. A. Marghoob, and G. Argenziano, J. Am. Acad. Dermatol. 74, 1093 (2016). https://doi.org/10.1016/j.jaad.2015.12.038
C. Rosendahl, M. Hishon, A. Cameron, S. Barksdale, D. Weedon, and H. Kittler, Dermatol. Pract. Concept. 4, 69 (2014). https://doi.org/10.5826/dpc.0402a15
T. Deinlein, G. Richtig, C. Schwab, F. Scarfi, E. Arzberger, I. Wolf, R. Hofmann-Wellenhof, and I. Zalaudek, J. German Soc. Dermatol. 14, 144 (2016). https://doi.org/10.1111/ddg.12903
M. Bleve, P. F. Capra, and P. Perugini, Magn. Reson. Med. 37, 185 (1997).
M. Rajadhyaksha, S. Gonzalez, J. M. Zavislan, R. R. Anderson, and R. H. Webb, J. Invest. Dermatol. 113, 293 (1999). https://doi.org/10.1046/j.1523-1747.1999.00690.x
S. Gonzalez, Actas Dermosifiliograf. 100, 59 (2009).
C. Longo, M. Ragazzi, M. Ragazzi, K. Nehal, A. Bennassar, G. Pellacani, and J. M. Guilera, Dermatol. Clin. 34, 497 (2016). https://doi.org/10.1016/j.det.2016.05.012
G. Pellacani, B. de Pace, C. Reggiani, A. M. Cesinaro, G. Argenziano, I. Zalaudek, H. P. Soyer, and C. Longo, Exp. Dermatol. 23, 414 (2014). https://doi.org/10.1111/exd.12417
A. M. Rollins, M. D. Kulkarni, S. Yazdanfar, R. Ungarunyawee, and J. A. Izatt, Opt. Express 3, 219 (1998). https://doi.org/10.1364/OE.3.000219
C. E. Saxer, J. F. de Boer, H. B. Park, Y. Zhao, Z. Chen, and J. S. Nelson, Opt. Lett. 25, 1355 (2000). https://doi.org/10.1364/OL.25.001355
J. Olsen, L. Themstrup, and G. B. Jemec, G. Ital. Dermatol. Venereol. 150, 603 (2015).
N. MacKinnon, F. Vasefi, N. Booth, and D. L. Farkas, Proc. SPIE 9711, 971111 (2016). https://doi.org/10.1117/12.2222415
B. Zhao and Y. He, Exp. Rev. Anticancer Ther. 10, 1797 (2010). https://doi.org/10.1586/era.10.154
D. J. Rohrbach, D. Muffoletto, J. Huihui, Saager R. K. Keymel, A. Paquette, J. Morgan, N. Zeitouni, and U. Sunar, Acad. Radiol. 21, 263 (2014). https://doi.org/10.1016/j.acra.2013.11.013
V. Neuschmelting, N. C. Burton, H. Lockau, A. Urich, S. Harmsen, V. Ntziachristos, and M. F. Kirchera, Photoacoustics 4, 1 (2016). https://doi.org/10.1016/j.pacs.2015.12.001
J. Müller, J. Hartmann, and C. Bert, Phys. Med. Biol. 61, 2646 (2016). https://doi.org/10.1088/0031-9155/61/7/2646
B. Petersen, P. A. Philipsena, and H. C. Wulf, Photochem. Photobiol. Sci. 13, 1123 (2014). https://doi.org/10.1039/C4PP00066H
O. Faust, U. R. Acharya, E. Y. K. Ng, T. J. Hong, and W. Yu, Infrared Phys. Technol. 66, 160 (2014). https://doi.org/10.1016/j.infrared.2014.06.001
J. P. North, M. C. Garrido, N. A. Kolaitis, and P. E. LeBoit, Am. J. Surg. Pathol. 38, 824 (2014). https://doi.org/10.1097/PAS.0000000000000189
E. G. Borisova, L. P. Angelova, and E. P. Pavlova, IEEE J. Sel. Top. Quant. Electron. 20, 211 (2014). https://doi.org/10.1109/JSTQE.2013.2280503
K. I. Zaytsev, K. G. Kudrin, V. E. Karasik, I. V. Reshetov, and S. O. Yurchenko, Appl. Phys. Lett. 106, 053702 (2015). https://doi.org/10.1063/1.4907350
K. I. Zaitsev, N. V. Chernomyrdin, K. G. Kudrin, I. V. Reshetov, and S. O. Yurchenko, Opt. Spectrosc. 119, 404 (2015). https://doi.org/10.7868/S0030403415090305
H. Ganster, P. Pinz, R. Rohrer, E. Wildling, M. Binder, and H. Kittler, IEEE Trans. Med. Imaging 20, 233 (2001). https://doi.org/10.1109/42.918473
A. Masood and A. A. Al-Jumaily, Int. J. Biomed. Imaging 2013, 1 (2013). https://doi.org/10.1155/2013/323268
Isasi A. Gola, B. Zapirain Garcia, and A. Mendez Zorrilla, Comput. Biol. Med. 41, 742 (2011). https://doi.org/10.1016/j.compbiomed.2011.06.010
B. P. Akhmedov and Z. M. Khasanova, Sovrem. Onkol. 4, 50 (2002).
S. Patel, M. Eluri, L. N. Boyers, C. Karimkhani, and R. Dellavalle, Dermatol. J. 21 (Nov. 9, 2014).
K. G. Kudrin, Onkokhirurgiya 6 (1), 71 (2014).
K. Wolff, L. Goldsmith, S. Katz, B. Gilchrest, A. S. Paller, and D. Leffell, Fitzpatrick’s Dermatology in General Medicine, 7th ed. (McGraw-Hill, New York, 2008).
V. I. Chissov, V. V. Starinskii, L. M. Aleksandrova, et al., Early Detection and Prevention of Skin Melanoma (MNIOI im. P.A. Gertsena Minzdrava Rossii, Moscow, 2013) [in Russian].
I. Deshin, E. Rimskaya, I. Apollonova, K. Kudrin, Z. Nursultanova, and A. Nikolaev, AIP Conf. Proc. 2140, 020017 (2019). https://doi.org/10.1063/1.5121942
E. N. Rimskaya, A. O. Schadko, I. A. Apollonova, A. P. Nikolaev, A. N. Briko, I. A. Deshin, P. U. Bereshnoy, K. G. Kudrin, K. I. Zaytsev, V. V. Tuchin, and I. V. Reshetov, Opt. Spectrosc. 126, 503 (2019). https://doi.org/10.1134/S0030400X19050230
K. G. Kudrin, O. V. Matorin, and I. V. Reshetov, Golova Sheya, No. 1, 9 (2014).
R. C. Gonzalez and R. E. Woods, Digital Image Processing Using MATLAB (Pearson, Prentice Hall, 2003).
R. C. Gonzalez and R. E. Woods, Digital Image Processing (Pearson, Prentice Hall, 2004).
S. V. Agapov, Photogrammetry of Scanner Images (Kartgeotsentr-Geodezizdat, Moscow, 1996) [in Russian].
S. Bazeille, I. Quidu, L. Jaulin, and J. P. Malkasse, CMM France, 16 (2006).
D. S. Rigel, J. Russak, and R. Friedman, Cancer J. Clin. 60, 301 (2010). https://doi.org/10.3322/caac.20074
A. M. Glazer, A. S. Farberg, R. R. Winkelmann, N. Tucker, and D. S. Rigel, Dermatol. Online J. 23, 13030/qt9xx2907s (2017).
M. Kutner, C. Nachtsheim, J. Neter, and W. Li, Applied Linear Statistical Models (McGraw-Hill/Irwin, Homewood, IL, 2004).
M. P. Cetingul and C. Herman, Phys. Med. Biol. 7, 5933 (2010). https://doi.org/10.1088/0031-9155/55/19/020
M. Arumi-Uria, N. S. McNutt, and B. Finnerty, Mod. Pathol. 16, 764 (2003).
R. L. Barnhill, J. A. Fine, G. C. Roush, and M. Berwick, Cancer 78, 427 (1996).
K. G. Kudrin, O. V. Matorin, and I. V. Reshetov, Onkokhirurgiya 5 (1), 8 (2013).
Yu. Yu. Sergeev and V. V. Mordovtseva, Kremlev. Med. Klin. Vestn., No. 1, 84 (2018).
D. Moreno-Ramirez, T. Ojeda-Vila, J. J. Rios-Martin, A. Nieto-Garcia, and L. Ferrandiz, Melanoma Res. 25, 450 (2015). https://doi.org/10.1097/CMR.0000000000000184
B. N. Akay, A. Okcu Heper, S. Clark, C. Erdem, C. O. Rosendahl, and H. Kittler, Int. J. Dermatol., No. 56, 1498 (2017). https://doi.org/10.1111/ijd.13728
S. Seidenari, C. Ferrari, S. Borsari, A. Fabiano, S. Bassoli, F. Giusti, G. Ponti, and C. Magnoni, Br. J. Dermatol. 171, 1006 (2014). https://doi.org/10.1111/bjd.12542
W. C. Black and W. C. Hunt, Am. J. Surg. Pathol., No. 14, 44 (1990).
N. V. Chernomyrdin, A. S. Kucheryavenko, G. S. Kolontaeva, G. M. Katyba, P. A. Karalkin, V. A. Parfenov, A. A. Gryadunova, N. E. Norkin, O. A. Smolyanskaya, O. V. Minin, I. V. Minin, V. E. Karasik, and K. I. Zaytsev, Proc. SPIE 10677, 106771Y (2018). https://doi.org/10.1117/12.2306132
Nguyen H. H. Pham, S. Hisatake, O. V. Minin, T. Nagatsuma, and I. V. Minin, APL Photon. 2, 056106 (2017). https://doi.org/10.1063/1.4983114
Funding
The development and testing of the experimental model screening system for pigmented neoplasms was supported by the Russian Foundation for Basic Research (project no. 18-38-00958). The development of metrological support and the thermographic studies of pigmented skin neoplasms were supported by the Russian Foundation for Basic Research (project no. 18-29-02099). The work performed at Sechenov First Moscow State Medical University was additionally supported by the Project 5-100, which is aimed at improving the competitiveness of Russian universities.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants involved in the study.
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Translated by T. Tkacheva
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Kudrin, K.G., Rimskaya, E.N., Apollonova, I.A. et al. Early Diagnosis of Skin Melanoma Using Several Imaging Systems. Opt. Spectrosc. 128, 824–834 (2020). https://doi.org/10.1134/S0030400X20060132
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DOI: https://doi.org/10.1134/S0030400X20060132