Modeling of Raman-Scattering Signals in Biological Tissues by Direct and Two-Step Approaches
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A search for an effective method of modelling of the Raman-spectroscopy problem in turbid (scattering) media has been performed taking into account the corresponding parameters of the detector and sample volume. A solution of the radiative-transfer equation by Monte-Carlo method underlies the proposed model. Two fundamental approaches to numerical modeling of Raman scattering are considered: the direct transport problem of Rayleigh and Raman photons at each point of the medium and the two-step model, in which a photon flux in the medium is calculated in the first stage, followed by generation of the corresponding number of Raman photons at each point.
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- 3.V. V. Tuchin, Handbook of Optical Biomedical Diagnostics (SPIE, Washington, 2002), p. 84.Google Scholar
- 4.I. Meglinski and A. V. Doronin, Advanced Biophotonics: Tissue Optical Sectioning, Ed. by V. V. Tuchin and R. K. Wang (Taylor Francis, London, 2012).Google Scholar