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MicroRNAs and cancer

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Abstract

The review is devoted to analyzing the data on the role of microRNAs in human tumor progression. The following topics are thoroughly discussed in the review: (1) general characteristics of microRNAs; (2) their expression pattern in human tumors and specificity of this expression; (3) the possible role of microRNAs as oncogenes and tumor growth suppressors; and (4) their participation in the processes responsible for the transformed phenotype of tumor cells; and (5) the role of microRNAs in early diagnostics of the disease and its prognosis.

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  1. Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia

    F. L. Kisseljov

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Original Russian Text © F.L. Kisseljov, 2014, published in Molekulyarnaya Biologiya, 2014, Vol. 48, No. 2, pp. 232–242.

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Kisseljov, F.L. MicroRNAs and cancer. Mol Biol 48, 197–206 (2014). https://doi.org/10.1134/S0026893314020083

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