Abstract
Several copies of the Penelope transposable element, previously described in Drosophila virilis, have been studied in different D. virilis strains and D. melanogaster strains transformed with P-based constructs bearing a full-size Penelope copy. Most Penelope copies in both species have large terminal inverted repeats (TIRs) and deletions of various sizes at the 5′ ends of their ORFs. Junctions between TIRs and ORFs usually have microhomologies of various lengths, which allowed a hypothesis explaining the emergence of these complex structures at the molecular level to be put forward. Most Penelope copies have a 34 bp long direct repeat at the ORF ends. Full-size and truncated Penelope copies are usually surrounded by target site duplications of various lengths.
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Original Russian Text © V.K. Ravin, M.B. Sukchev, E.S. Zelentsova, N.G. Shostak, M.B. Evgen’ev, 2009, published in Molekulyarnaya Biologiya, 2009, Vol. 43, No. 2, pp. 357–367.
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Ravin, V.K., Sukchev, M.B., Zelentsova, E.S. et al. Structural and functional analysis of a new retrotransposon class in Drosophila species. Mol Biol 43, 329–338 (2009). https://doi.org/10.1134/S0026893309020150
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DOI: https://doi.org/10.1134/S0026893309020150