Molecular Biology

, Volume 43, Issue 2, pp 301–312 | Cite as

Disaccharide nucleosides as an important group of natural compounds

  • E. V. Efimtseva
  • I. V. Kulikova
  • S. N. MikhailovEmail author
To the Anniversary of the Institute of Molecular Biology


The main structural features of disaccharide nucleosides, an important group of natural compounds, are reviewed. The preparation and properties of modified oligonucleotides constructed on their basis and the incorporation of reactive groups are summarized. Several examples are given for the use of the compounds to investigate the enzymes of nucleic acid metabolism.

Key words

disaccharide nucleosides oligonucleotides structure physicochemical and biological properties affinity modification enzymes of nucleic acid biosynthesis 


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Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • E. V. Efimtseva
    • 1
  • I. V. Kulikova
    • 1
  • S. N. Mikhailov
    • 1
    Email author
  1. 1.Engelhardt Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia

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