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Role of recombination occurring during DNA replication

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Abstract

Unequal crossing over between direct DNA repeats of sister chromosomes occurs during DNA replication in Escherichia coli. Such exchanges yield tandem duplications and thereby increase the expression of the genes involved. Nonhomologous cohesion of sister chromosomes and unequal crossing over were assumed to take place when the replication fork stops. When the replication forks moves continuously, homologous exchanges between sister chromosomes ensure their postreplication repair.

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Authors and Affiliations

  1. State Research Center GosNIIgenetika, Moscow, 117545, Russia

    V. V. Sukhodolets

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  1. V. V. Sukhodolets
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Original Russian Text © V.V. Sukhodolets, 2006, published in Molekulyarnaya Biologiya, 2006, Vol. 40, No. 2, pp. 369–371.

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Sukhodolets, V.V. Role of recombination occurring during DNA replication. Mol Biol 40, 324–326 (2006). https://doi.org/10.1134/S0026893306020191

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  • DOI: https://doi.org/10.1134/S0026893306020191

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